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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Hydroxylation of 5-methylcytosine by TET2 maintains the active stat...
Published: May, 2012
Abstract: Differentiation is accompanied by extensive epigenomic reprogramming, leading to the repression of stemness factors and the transcriptional mainten... Read more »
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DNA shearing Bioruptor
Genome-wide search reveals the existence of a limited number of thy...
Published: May, 2012
Abstract: Thyroid hormone (T3) has a major influence on cerebellum post-natal development. The major phenotypic landmark of exposure to low levels of T3 duri... Read more »
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Bioruptor Chromatin Shearing
piRNA-mediated transgenerational inheritance of an acquired trait.
Published: May, 2012
Abstract: The maintenance of genome integrity is an essential trait to the successful transmission of genetic information. In animal germ cells, piRNAs guide... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Environmentally induced epigenetic transgenerational inheritance of...
Published: May, 2012
Abstract: The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was inves... Read more »
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Antibody
Disruption of RAB40AL function leads to Martin-Probst syndrome, a r...
Published: May, 2012
Abstract: Background and aim Martin-Probst syndrome (MPS) is a rare X-linked disorder characterised by deafness, cognitive impairment, short stature and dist... Read more »
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DNA shearing Bioruptor
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors...
Published: May, 2012
Abstract: Increasing evidence suggests that chromatin modifications have important roles in modulating constitutive or alternative splicing. Here we demonstr... Read more »
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Bioruptor Chromatin Shearing
Characterization of glomerular diseases using proteomic analysis of...
Published: May, 2012
Abstract: The application of molecular techniques to characterize clinical kidney biopsies has the potential to provide insights into glomerular diseases tha... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
Clinical implications and molecular mechanisms of immunoparalysis a...
Published: May, 2012
Abstract: OBJECTIVE: We used a whole blood assay to characterize the immune system's response after cardiopulmonary bypass (CPB) in children to identify the ... Read more »
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LowCell ChIP kit
SOX7 regulates the expression of VE-cadherin in the haemogenic endo...
Published: May, 2012
Abstract: At early stages of vertebrate ontogeny, blood and endothelial cells develop from a common mesodermal progenitor, the haemangioblast. Upon haematopo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Kdm2b promotes induced pluripotent stem cell generation by facilita...
Published: May, 2012
Abstract: Transcription-factor-directed reprogramming from somatic cells to induced pluripotent stem cells (iPSCs) is by nature an epigenetic process of cell... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Cell type-specific chromatin immunoprecipitation from multicellular...
Published: May, 2012
Abstract: This protocol describes the batch isolation of tissue-specific chromatin for immunoprecipitation (BiTS-ChIP) for analysis of histone modifications,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq
Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 ...
Published: May, 2012
Abstract: Although soy phytoestrogens have been postulated to exert a protective effect against breast cancer, the attendant mechanisms, in particular epigen... Read more »
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DNA shearing Bioruptor MagMeDIP kit
Antiproliferative Effects of DNA Methyltransferase 3B Depletion Are...
Published: May, 2012
Abstract: Silencing of genes by hypermethylation contributes to cancer progression and has been shown to occur with increased frequency at specific genomic l... Read more »
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Bioruptor Cell Lysis
Targeted inhibition of TCF activity promotes syndecan-2 expression ...
Published: May, 2012
Abstract: Alterations of Wnt signaling appear to be involved in the pathogenesis of osteosarcoma presenting mutations of Adenomatous Polyposis Coli and epige... Read more »
LINT, a Novel dL(3)mbt-Containing Complex, Represses Malignant Brai...
Published: May, 2012
Abstract: Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval brains. Recently, the derepression of different gene cl... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Dynamic deposition of histone variant h3.3 accompanies developmenta...
Published: May, 2012
Abstract: In animals, replication-coupled histone H3.1 can be distinguished from replication-independent histone H3.3. H3.3 variants are enriched at active g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Bet hedging in yeast by heterogeneous, age-correlated expression of...
Published: May, 2012
Abstract: Genetically identical cells grown in the same culture display striking cell-to-cell heterogeneity in gene expression and other traits. A crucial ch... Read more »
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Bioruptor
Influence of Neonatal Hypothyroidism on Hepatic Gene Expression and...
Published: May, 2012
Abstract: Not Available Read more »
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Master Mix
Alterations of glucose metabolism in Escherichia coli mutants defec...
Published: April, 2012
Abstract: The effects of reduced efficiency of proton-motive force (pmf) generation on glucose metabolism were investigated in Escherichia coli respiratory-c... Read more »
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Cell Lysis Enzymatic Assay
Transient neonatal diabetes mellitus gene Zac1 impairs insulin secr...
Published: April, 2012
Abstract: Biallelic expression of the imprinted gene ZAC1/PLAGL1 underlies ∼60% of all cases of transient neonatal diabetes mellitus (TNDM) which present wit... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The SEC family of RNA Polymerase II elongation factors: gene target...
Published: April, 2012
Abstract: The elongation stage of transcription is highly regulated in metazoans. We previously purified the AFF1/AFF4-containing Super Elongation Complex (S... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Lxrα Regulates the Androgen Response in Prostate Epithelium.
Published: April, 2012
Abstract: Benign prostatic hyperplasia is a nonmalignant enlargement of the prostate that commonly occurs in older men. We show that liver X receptor (Lxr)-α... Read more »
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Antibody
Epigenetic modifications of GABAergic interneurons are associated w...
Published: April, 2012
Abstract: Human studies suggest that a variety of prenatal stressors are related to high risk for cognitive and behavioral abnormalities associated with psyc... Read more »
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Antibody
The transcriptional and epigenomic foundations of ground state plur...
Published: April, 2012
Abstract: Mouse embryonic stem (ES) cells grown in serum exhibit greater heterogeneity in morphology and expression of pluripotency factors than ES cells cul... Read more »
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Antibody H3K4me3 (C15410003)
iASPP inhibits p53-independent apoptosis by inhibiting transcriptio...
Published: April, 2012
Abstract: The ability to induce apoptosis is the most important tumor-suppression function of p53. Inhibitory member of apoptosis-stimulating protein of p53 ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Bloom's Syndrome and PICH Helicases Cooperate with Topoisomerase II...
Published: April, 2012
Abstract: Centromeres are specialized chromosome domains that control chromosome segregation during mitosis, but little is known about the mechanisms underly... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dendritic Cells Activated by IFN-γ/STAT1 Express IL-31 Receptor and...
Published: April, 2012
Abstract: IL-31 is a T cell-derived cytokine that signals via a heterodimeric receptor composed of IL-31Rα and oncostatin M receptor β. Although several stud... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
Uncovering cis-regulatory sequence requirements for context specifi...
Published: April, 2012
Abstract: The regulation of gene expression is mediated at the transcriptional level by enhancer regions that are bound by sequence specific transcription fa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome Wide Analysis Of Pax8 Binding Provides New Insights Into Thy...
Published: April, 2012
Abstract: ABSTRACT: BACKGROUND: The transcription factor Pax8 is essential for the differentiation of thyroid cells. However, there are few data on genes tra... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Global analysis of the regulon of the transcriptional repressor Lex...
Published: April, 2012
Abstract: The DNA damage response is crucial for bacterial survival. The transcriptional repressor LexA is a key component of the SOS response, the main mech... Read more »
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Bioruptor Chromatin Shearing ChIP-seq IPure kit

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