Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Post-transcriptional spliceosomes are retained in nuclear speckles ...
Published: August, 2012

Abstract: There is little quantitative information regarding how much splicing occurs co-transcriptionally in higher eukaryotes, and it remains unclear where... Read more »

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Bioruptor
Androgen Receptor Antagonism by Divalent Ethisterone Conjugates in ...
Published: August, 2012

Abstract: Sustained treatment of prostate cancer with androgen receptor (AR) antagonists can evoke drug resistance, leading to castrate-resistant disease. El... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Erg and AP-1 as determinants of glucocorticoid response in acute ly...
Published: August, 2012

Abstract: Glucocorticoids (GCs) are among the most widely prescribed medications in clinical practice. The beneficial effects of GCs in acute lymphoblastic l... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Selective targeting of the repressive transcription factors YY1 and...
Published: August, 2012

Abstract: Quiescent HIV-1 infection of resting CD4+ T cells is an obstacle to eradication of HIV-1 infection. These reservoirs are maintained, in part, by re... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
DDR complex facilitates global association of RNA polymerase V to p...
Published: August, 2012

Abstract: The plant-specific DNA-dependent RNA polymerase V (Pol V) evolved from Pol II to function in an RNA-directed DNA methylation pathway. Here, we have... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Generation of DNA single-strand displacement by compromised nucleot...
Published: August, 2012

Abstract: Nucleotide excision repair (NER) is a precisely coordinated process essential to avoid DNA damage-induced cellular malfunction and mutagenesis. Her... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
FM19G11 Favors Spinal Cord Injury Regeneration and Stem Cell Self-R...
Published: August, 2012

Abstract: Spinal cord injury is a major cause of paralysis with no currently effective therapies. Induction of self-renewal and proliferation of endogenous r... Read more »

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Bioruptor Cell Lysis Enzymatic Assay
Defining the core Arabidopsis thaliana root microbiome.
Published: August, 2012

Abstract: Land plants associate with a root microbiota distinct from the complex microbial community present in surrounding soil. The microbiota colonizing t... Read more »

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Bioruptor
Carm1 Regulates Pax7 Transcriptional Activity through MLL1/2 Recrui...
Published: August, 2012

Abstract: In skeletal muscle, asymmetrically dividing satellite stem cells give rise to committed satellite cells that transcribe the myogenic determination ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Interaction of nucleolin with ribosomal RNA genes and its role in R...
Published: August, 2012

Abstract: Nucleolin is a multi-functional nucleolar protein that is required for ribosomal RNA gene (rRNA) transcription in vivo, but the mechanism by which ... Read more »

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Antibody
Functional Cooperation between Human Adenovirus Type 5 Early Region...
Published: August, 2012

Abstract: Human adenovirus type 5 (HAdV5) E4orf6 (early region 4 open reading frame 6 protein) is a multifunctional early viral protein promoting efficient r... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic Silencing of Cd8 Genes by ThPOK-Mediated Deacetylation d...
Published: August, 2012

Abstract: Intrathymic CD4/CD8 differentiation is a process that establishes the mutually exclusive expression profiles of the CD4 and CD8 T cell lineage. The... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin Immunoprecipitation Analysis of Xenopus Embryos
Published: August, 2012

Abstract: Chromatin immunoprecipitation (ChIP) is a powerful technique to study epigenetic regulation and transcription factor binding events in the nucleus.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and M...
Published: July, 2012

Abstract: Genomic rearrangements commonly occur in many types of cancers and often initiate or alter the progression of disease. Here we describe an in vivo ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Mixture models and wavelet transforms reveal high confidence RNA-pr...
Published: July, 2012

Abstract: The Photo-Activatable Ribonucleoside-enhanced CrossLinking and ImmunoPrecipitation (PAR-CLIP) method was recently developed for global identificati... Read more »

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Bioruptor Cell Lysis
Retinoic acid receptors recognize the mouse genome through binding ...
Published: July, 2012

Abstract: Retinoic acid receptors (RARs) heterodimerize with retinoid X receptors (RXRs) and bind to RA response elements (RAREs) in the regulatory regions o... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
ChAP-MS: A Method for Identification of Proteins and Histone Posttr...
Published: July, 2012

Abstract: The field of epigenomics has been transformed by chromatin immunoprecipitation approaches that provide for the localization of a defined protein or... Read more »

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Bioruptor Chromatin Shearing
Administration of vorinostat disrupts HIV-1 latency in patients on ...
Published: July, 2012

Abstract: Despite antiretroviral therapy, proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to curing the infectio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Expression of endogenous retroviruses is negatively regulated by th...
Published: July, 2012

Abstract: Rex1/Zfp42 is a Yy1-related zinc-finger protein whose expression is frequently used to identify pluripotent stem cells. We show that depletion of R... Read more »

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Bioruptor Cell Lysis Western Blot
Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms t...
Published: July, 2012

Abstract: Protein kinase CK2 promotes cell survival and the activity of this kinase is elevated in several cancers including chronic myeloid leukaemia. We ha... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Curcumin induces human cathelicidin antimicrobial peptide gene expr...
Published: July, 2012

Abstract: The vitamin D receptor (VDR) mediates the pleiotropic biologic effects of 1α,25 dihydroxy-vitamin D(3). Recent in vitro studies suggested that curc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Role of SUMOylation in full antiestrogenicity.
Published: July, 2012

Abstract: The selective estrogen receptor downregulator (SERD) fulvestrant can be used as second line treatment in patients relapsing after treatment with ta... Read more »

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Bioruptor Cell Lysis
The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine ...
Published: July, 2012

Abstract: Fbxl10 (Jhdm1b/Kdm2b) is a conserved and ubiquitously expressed member of the JHDM (JmjC-domain-containing histone demethy-lase) family. Fbxl10 was... Read more »

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Antibody H3K27me3 (C15410069)
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in i...
Published: July, 2012

Abstract: Mutations in the genes encoding isocitrate dehydrogenase, IDH1 and IDH2, have been reported in gliomas, myeloid leukemias, chondrosarcomas and thyr... Read more »

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DNA shearing Bioruptor
Up-regulation of 2-oxoglutarate dehydrogenase as a stress response.
Published: July, 2012

Abstract: 2-Oxoglutarate dehydrogenase multienzyme complex (OGDHC) operates at a metabolic cross-road, mediating Ca(2+)- and ADP-dependent signals in mitocho... Read more »

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Bioruptor Cell Lysis
Chromatin measurements reveal contributions of synthesis and decay ...
Published: July, 2012

Abstract: Messenger RNA levels in eukaryotes are controlled by multiple consecutive regulatory processes, which can be classified into two layers: primary tr... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
A comparison of transcriptome and epigenetic status between closely...
Published: July, 2012

Abstract: Difference in the level of expression of genes is one of the factors contributing to plant phenotype. As well as being under genetic control, gene ... Read more »

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Antibody
An epigenetic silencing pathway controlling T helper 2 cell lineage...
Published: July, 2012

Abstract: During immune responses, naive CD4+ T cells differentiate into several T helper (TH) cell subsets under the control of lineage-specifying genes. Th... Read more »
Supp. mat - An epigenetic silencing pathway controlling T helper 2 ...
Published: July, 2012

Abstract: During immune responses, naive CD4+ T cells differentiate into several T helper (TH) cell subsets under the control of lineage-specifying genes. Th... Read more »
Dynamic Changes in Ezh2 Gene Occupancy Underlie Its Involvement in ...
Published: July, 2012

Abstract: Background: The polycomb group protein Ezh2 is an epigenetic repressor of transcription originally found to prevent untimely differentiation of plu... Read more »

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Antibody

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