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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Optimization of CRISPR/Cas9 genome editing for loss-of-function in ...
Published: December, 2017
Abstract: The advent of CRISPR/Cas9 has made genome editing possible in virtually any organism, including those not previously amenable to genetic manipulati... Read more »
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Antibody
Single-cell absolute contact probability detection reveals chromoso...
Published: November, 2017
Abstract: At the kilo- to megabase pair scales, eukaryotic genomes are partitioned into self-interacting modules or topologically associated domains (TADs) t... Read more »
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Antibody
The histone code reader Spin1 controls skeletal muscle development
Published: November, 2017
Abstract: While several studies correlated increased expression of the histone code reader Spin1 with tumor formation or growth, little is known about physio... Read more »
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Antibody IP-Star Compact
DNA methylation signatures follow preformed chromatin compartments ...
Published: November, 2017
Abstract: Storage of chromatin in restricted nuclear space requires dense packing while ensuring DNA accessibility. Thus, different layers of chromatin organ... Read more »
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Antibody
ChIP-Seq analysis identifies p27(Kip1)-target genes involved in cel...
Published: November, 2017
Abstract: The protein p27Kip1 (p27), a member of the Cip-Kip family of cyclin-dependent kinase inhibitors, is involved in tumorigenesis and a correlation bet... Read more »
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IPure kit
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesen...
Published: November, 2017
Abstract: RATIONALE: Human cardiac mesenchymal cells (CMSCs) are a therapeutically relevant primary cell population. Diabetes mellitus compromises CMSC fu... Read more »
FBXO32 promotes microenvironment underlying epithelial-mesenchymal ...
Published: November, 2017
Abstract: The set of events that convert adherent epithelial cells into migratory cells are collectively known as epithelial-mesenchymal transition (EMT). EM... Read more »
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Antibody
In Situ Fixation Redefines Quiescence and Early Activation of Skele...
Published: November, 2017
Abstract: Summary State of the art techniques have been developed to isolate and analyze cells from various tissues, aiming to capture their in viv... Read more »
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Antibody Premium RRBS Kit
PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumor...
Published: November, 2017
Abstract: In NSCLC alterations in PDGF receptors are markers of worst prognosis and efficient targeting of these receptors is yet to be achieved. In this stu... Read more »
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IPure kit
Data on novel DNA methylation changes induced by valproic acid in h...
Published: November, 2017
Abstract: Valproic acid (VPA) is a widely prescribed antiepileptic drug in the world. Despite its pharmacological importance, it may cause liver toxicity and... Read more »
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MagMeDIP kit IPure kit
GATA2/3-TFAP2A/C transcription factor network couples human pluripo...
Published: November, 2017
Abstract: To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophectoderm character... Read more »
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Antibody
5-Methylcytosine RNA Methylation in Arabidopsis Thaliana
Published: November, 2017
Abstract: 5-Methylcytosine (m5C) is a well-characterized DNA modification, and is also predominantly reported in abundant non-coding RNAs in both prokaryotes... Read more »
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Antibody
An endosiRNA-Based Repression Mechanism Counteracts Transposon Acti...
Published: November, 2017
Abstract: Erasure of DNA methylation and repressive chromatin marks in the mammalian germline leads to risk of transcriptional activation of transposable ele... Read more »
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Microplex Library Preparation kit
Transcription Factor YY1 Modulates Lung Cancer Progression by Activ...
Published: November, 2017
Abstract: Lung cancer is the leading cause of cancer-related death worldwide. Despite the advancement in surgery and chemotherapy, the prognosis of patients ... Read more »
Epigenetic control of epilepsy target genes contributes to a cellul...
Published: October, 2017
Abstract: Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable l... Read more »
Drug-tunable multidimensional synthetic gene control using inducibl...
Published: October, 2017
Abstract: The nuclease-deactivated variant of CRISPR-Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA sequen... Read more »
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Antibody
Saliva as a Blood Alternative for Genome-Wide DNA Methylation Profi...
Published: October, 2017
Abstract: Background: Interrogation of DNA methylation profiles hold promise for improved diagnostics, as well as the delineation of the aetiology for common... Read more »
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IP-Star Compact
Alterations in the placental methylome with maternal obesity and ev...
Published: October, 2017
Abstract: The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complicat... Read more »
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Antibody
Single-Molecule Sequencing Reveals the Chromosome-Scale Genomic Arc...
Published: October, 2017
Abstract: The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegan... Read more »
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Megaruptor
Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valpr...
Published: October, 2017
Abstract: Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs in the world. Despite its pharmacological importance, it may cause liv... Read more »
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MagMeDIP kit IPure kit
Individual effects of the copia and gypsy enhancer and insulator on...
Published: October, 2017
Abstract: Enhancers and insulators are involved in the regulation of gene expression, but the basic underlying mechanisms of action of these elements are unk... Read more »
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ChIP-qPCR
Distinguishing States of Arrest: Genome-Wide Descriptions of Cellul...
Published: October, 2017
Abstract: Regenerative potential in adult stem cells is closely associated with the establishment of-and exit from-a temporary state of quiescence. Emerging ... Read more »
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LowCell ChIP kit IPure kit
Genome methylation and regulatory functions for hypoxic adaptation...
Published: October, 2017
Abstract: Tibetan chickens have unique adaptations to the extreme high-altitude environment that they inhabit. Epigenetic DNA methylation affects many biolog... Read more »
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MagMeDIP kit
Discovery of a selective catalytic p300/CBP inhibitor that targets ...
Published: October, 2017
Abstract: The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), is a major epi... Read more »
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Bioruptor IP-Star Compact
The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and...
Published: October, 2017
Abstract: Genomic imprinting is an allelic gene expression phenomenon primarily controlled by allele-specific DNA methylation at the imprinting control regio... Read more »
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Antibody
The mixed lineage leukemia 4 (MLL4) methyltransferase complex is in...
Published: October, 2017
Abstract: Sma and Mad related (SMAD)-mediated Transforming Growth Factor β (TGF-β) and Bone Morphogenetic Protein (BMP) signaling is required for v... Read more »
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Antibody
De novo PacBio long-read and phased avian genome assemblies correct...
Published: October, 2017
Abstract: Reference-quality genomes are expected to provide a resource for studying gene structure, function, and evolution. However, often genes of interest... Read more »
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Megaruptor
BET-bromodomain inhibitors modulate epigenetic patterns at the diac...
Published: October, 2017
Abstract: BACKGROUND AND PURPOSE: Fibrosis is a frequent adverse effect of radiotherapy and no effective treatments are currently available to prevent or re... Read more »
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IP-Star Compact
Rapid Communication: The correlation between histone modifications ...
Published: October, 2017
Abstract: Histone modification is a well-known epigenetic mechanism involved in regulation of gene expression; however, it has been poorly studied in adipose... Read more »
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Antibody LowCell ChIP kit
TET2- and TDG-mediated changes are required for the acquisition of ...
Published: September, 2017
Abstract: The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MAC... Read more »
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Antibody LowCell ChIP kit

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