Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Senescence-associated reprogramming promotes cancer stemness.
Published: January, 2018

Abstract: Cellular senescence is a stress-responsive cell-cycle arrest program that terminates the further expansion of (pre-)malignant cells. Key signalling... Read more »

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Antibody
APRDX1 mutant allele causes a MMACHC secondary epimutation in cblC ...
Published: January, 2018

Abstract: To date, epimutations reported in man have been somatic and erased in germlines. Here, we identify a cause of the autosomal recessive cblC class of... Read more »

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IP-Star Histone ChIP kit
Copper induces expression and methylation changes of early developm...
Published: January, 2018

Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »

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MagMeDIP kit
STAT5BN642H is a driver mutation for T cell neoplasia
Published: January, 2018

Abstract: STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and... Read more »

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Antibody
Genome-wide analysis of day/night DNA methylation differences in Po...
Published: January, 2018

Abstract: DNA methylation is an important mechanism of epigenetic modification. Methylation changes during stress responses and developmental processes have ... Read more »

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MagMeDIP kit Antibody
Obligatory and facilitative allelic variation in the DNA methylome ...
Published: January, 2018

Abstract: Integrating epigenetic data with genome-wide association study (GWAS) results can reveal disease mechanisms. The genome sequence itself also&n... Read more »

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MagMeDIP kit Antibody
MLL2 conveys transcription-independent H3K4 trimethylation in oocytes
Published: January, 2018

Abstract: Histone 3 K4 trimethylation (depositing H3K4me3 marks) is typically associated with active promoters yet paradoxically occurs at untranscribed doma... Read more »

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Antibody Microplex Library Preparation kit
TBR2 antagonizes retinoic acid dependent neuronal differentiation b...
Published: January, 2018

Abstract: During cerebral cortex development, neural progenitors are required to elaborate a variety of cell differentiation signals to which they are contin... Read more »
Chromatin Immunoprecipitation Assay in the Hyperthermoacidophilic C...
Published: January, 2018

Abstract: Chromatin immunoprecipitation (ChIP) is a powerful method used for identifying genome-wide DNA-protein interactions in vivo. A large number of esse... Read more »

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IPure kit
Detection of Hermetia illucens by real-time PCR
Published: January, 2018

Abstract: Insects are rich in proteins and could be an alternative source of macronutrients to feed animals and humans. Over the past few years, numerous com... Read more »

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Master Mix
Antioxydation And Cell Migration Genes Are Identified as Potential ...
Published: January, 2018

Abstract: Basal-like breast cancers are among the most aggressive cancers and effective targeted therapies are still missing. In order to identify new therap... Read more »

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MethylCap
Impact of Lactobacillus plantarum ST-III on the composition of infa...
Published: January, 2018

Abstract: Several studies have demonstrated the effect of probiotics on prevention of diseases in infants. However, the mechanisms remain not fully addressed... Read more »

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Master Mix
RNA-Based dCas9–VP64 System Improves the Viability of Cryopreserved...
Published: January, 2018

Abstract: Regenerative therapies require availability of an abundant healthy cell source which can be achieved by e±cient cryopreservation techniques.... Read more »

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Antibody CRISPR
Epigenetic alterations in TRAMP mice: epigenome DNA methylation pro...
Published: January, 2018

Abstract: Purpose: We investigated the genomic DNA methylation profile of prostate cancer in transgenic adenocarcinoma of the mouse prostate (TRAMP) cancer m... Read more »

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MagMeDIP kit
Environmental toxicant induced epigenetic transgenerational inherit...
Published: January, 2018

Abstract: Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Sy... Read more »

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Antibody
Cancer cell specific inhibition of Wnt/β-catenin signaling by force...
Published: January, 2018

Abstract: Use of the diabetes type II drug Metformin is associated with a moderately lowered risk of cancer incidence in numerous tumor entities. Studying th... Read more »

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Antibody
Neonatal exposure to hyperoxia leads to persistent disturbances in ...
Published: January, 2018

Abstract: Background: Early pulmonary oxygen exposure is one of the most important factors implicated in the development of bronchopulmonary dysplasia (BPD).... Read more »

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Antibody
Analysis of DNA methylome and transcriptome profiling following Gib...
Published: January, 2018

Abstract: The present work investigated a comprehensive genome-wide landscape of DNA methylome and its relationship with transcriptome upon gibberellin A3 (G... Read more »

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MagMeDIP kit Antibody
Isl1 mediates mesenchymal expansion in the developing external geni...
Published: January, 2018

Abstract: Genital malformations are among the most common human birth defects, and both genetic and environmental factors can contribute to these malformatio... Read more »
BRACHYURY directs histone acetylation to target loci during mesoder...
Published: January, 2018

Abstract: T-box transcription factors play essential roles in multiple aspects of vertebrate development. Here, we show that cooperative function of BRACHYUR... Read more »

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Antibody
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: December, 2017

Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »

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Bioruptor ChIP-seq
(Po)STAC (Polycistronic SunTAg modified CRISPR) enables live-cell a...
Published: December, 2017

Abstract: CRISPR/dCas9-based labeling has allowed direct visualization of genomic regions in living cells. However, poor labeling efficiency and signal-to-ba... Read more »

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Antibody
Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest ...
Published: December, 2017

Abstract: Cockayne syndrome (CS) is caused by mutations in CSA and CSB. The CSA and CSB proteins have been linked to both promoting transcription-coupled rep... Read more »

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Antibody
The L1 adhesion molecule normalizes neuritogenesis in Rett syndrome...
Published: December, 2017

Abstract: Therapeutic intervention is an important need in ameliorating the severe consequences of Rett Syndrome (RTT), a neurological disorder caused by mut... Read more »

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Antibody
Repeated methamphetamine and modafinil induce differential cognitiv...
Published: December, 2017

Abstract: Methamphetamine (METH) and modafinil are psychostimulants with different long-term cognitive profiles: METH is addictive and leads to cogniti... Read more »

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DNA shearing Bioruptor
Oestrogen Receptor-α binds the FOXP3 promoter and modulates regulat...
Published: December, 2017

Abstract: Oestrogen controls Foxp3 expression in regulatory T cells (Treg cells) via a mechanism thought to involve oestrogen receptor alpha (ERα), but... Read more »

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Antibody
Dual SIRT1 expression patterns strongly suggests its bivalent role ...
Published: December, 2017

Abstract: Breast cancer is the most common cancer in women, and the leading cause of cancer death in women worldwide. SIRT1 (silent mating type information r... Read more »

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Antibody
Functional dissection of Drosophila melanogaster SUUR protein influ...
Published: December, 2017

Abstract: Background In eukaryotes, heterochromatin replicates late in S phase of the cell cycle and contains specific covalent modifications of histones.... Read more »

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Microplex Library Preparation kit True MicroChIP kit
Super enhancer associated RAI14 is a new potential biomarker in lun...
Published: December, 2017

Abstract: Tyrosine kinase inhibitors (TKIs) are widely used to treat lung adenocarcinoma patients with EGFR mutations or ALK-fusions. However, patients with ... Read more »

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Bioruptor

 


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