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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Intestinal hypoxia-inducible transcription factors are essential fo...
Published: February, 2009
Abstract: Iron deficiency and iron overload are among the most prevalent nutritional disorders worldwide. Duodenal cytochrome b (DcytB) and divalent metal tr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The reelin and GAD67 promoters are activated by epigenetic drugs th...
Published: February, 2009
Abstract: The epigenetic down-regulation of genes is emerging as a possible underlying mechanism of the GABAergic neuron dysfunction in schizophrenia. For ex... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Nuclear factor-kappaB binds to the Epstein-Barr Virus LMP1 promoter...
Published: February, 2009
Abstract: The latent membrane protein 1 (LMP1) oncogene carried by Epstein-Barr virus (EBV) is essential for transformation and maintenance of EBV-immortaliz... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic ...
Published: February, 2009
Abstract: Patched (Ptch) heterozygous mice develop medulloblastoma (MB) and rhabdomyosarcoma (RMS) resembling the corresponding human tumors. We have previou... Read more »
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MeDIP kit
Survival motor neuron gene 2 silencing by DNA methylation correlate...
Published: January, 2009
Abstract: Spinal muscular atrophy (SMA), a common neuromuscular disorder, is caused by homozygous absence of the survival motor neuron gene 1 (SMN1), while t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependen...
Published: January, 2009
Abstract: Members of the sirtuin (SIRT) family of NAD-dependent deacetylases promote longevity in multiple organisms. Deficiency of mammalian SIRT6 leads to ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Distinct differences in chromatin structure at subtelomeric X and Y...
Published: January, 2009
Abstract: In Saccharomyces cerevisiae, all ends of telomeric DNA contain telomeric repeats of (TG(1-3)), but the number and position of subtelomeric X and Y'... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Hybrid selection of discrete genomic intervals on custom-designed m...
Published: January, 2009
Abstract: Complementary techniques that deepen information content and minimize reagent costs are required to realize the full potential of massively paralle... Read more »
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DNA shearing Bioruptor
Cell-free circulating DNA: diagnostic value in patients with testic...
Published: January, 2009
Abstract: PURPOSE: Increased levels of cell-free circulating DNA have been described in various malignancies as a diagnostic and prognostic biomarker. We ana... Read more »
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DNA shearing Bioruptor
Tandem ChoRE and CCAAT motifs and associated factors regulate Txnip...
Published: January, 2009
Abstract: BACKGROUND: Thioredoxin interacting protein (Txnip) is a multifunctional protein involved in regulation of cell cycle events and cellular metabolis... Read more »
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Antibody
TBP2 is a substitute for TBP in Xenopus oocyte transcription.
Published: January, 2009
Abstract: BACKGROUND: TATA-box-binding protein 2 (TBP2/TRF3) is a vertebrate-specific paralog of TBP that shares with TBP a highly conserved carboxy-terminal... Read more »
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Antibody
The chromodomain of LIKE HETEROCHROMATIN PROTEIN 1 is essential for...
Published: January, 2009
Abstract: Polycomb group (PcG) proteins are essential to maintain gene expression patterns during development. Transcriptional repression by PcG proteins inv... Read more »
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Antibody LowCell ChIP kit
TIPT2 and geminin interact with basal transcription factors to syne...
Published: January, 2009
Abstract: BACKGROUND: The re-replication inhibitor Geminin binds to several transcription factors including homeodomain proteins, and to members of the polyc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Epigenetic engineering of ribosomal RNA genes enhances protein prod...
Published: January, 2009
Abstract: Selection of mammalian high-producer cell lines remains a major challenge for the biopharmaceutical manufacturing industry. Ribosomal RNA (rRNA) ge... Read more »
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Antibody Master Mix
Methylated DNA immunoprecipitation and microarray-based analysis: d...
Published: January, 2009
Abstract: The methylated DNA immunoprecipitation microarray (MeDIP-chip) is a genome-wide, high-resolution approach to detect DNA methylation in whole genome... Read more »
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DNA shearing Bioruptor Antibody
The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required...
Published: January, 2009
Abstract: BACKGROUND: SET-domain proteins are histone lysine (K) methyltransferases (HMTase) implicated in defining transcriptionally permissive or repressiv... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Approaches to determine expression of inflammatory cytokines.
Published: January, 2009
Abstract: There is an increasing awareness of the role of inflammation in cancer. Immune responses can limit the growth of some tumors, but paradoxically, ma... Read more »
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Bioruptor Tissue Homogenization
Cooperation between NRF-2 and YY-1 transcription factors is essenti...
Published: January, 2009
Abstract: BACKGROUND: Many mammalian genes are organized as bidirectional (head-to-head) gene pairs with the two genes separated only by less than 1 kb. The ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Core promoter acetylation is not required for high transcription fr...
Published: January, 2009
Abstract: BACKGROUND: Acetylation of promoter nucleosomes is tightly correlated and mechanistically linked to gene activity. However, transcription is not ne... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Remodeling of the chromatin structure of the facioscapulohumeral mu...
Published: January, 2009
Abstract: BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder associated with the partial deletion of i... Read more »
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Antibody
Improving the efficiency of genomic loci capture using oligonucleot...
Published: January, 2009
Abstract: BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants o... Read more »
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DNA shearing Bioruptor
Monodispersity of recombinant Cre recombinase correlates with its e...
Published: January, 2009
Abstract: BACKGROUND: Cre recombinase is a common reagent used for the in vivo on/off switching of the expression of target genes flanked by loxP sites. In p... Read more »
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Bioruptor Cell Lysis
Multiple histone modifications in euchromatin promote heterochromat...
Published: January, 2009
Abstract: BACKGROUND: Methylation of lysine 79 on histone H3 by Dot1 is required for maintenance of heterochromatin structure in yeast and humans. However, t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 s...
Published: January, 2009
Abstract: The Sry-related high mobility group box transcription factor Sox17 is required for diverse developmental processes including endoderm formation, va... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The protein tyrosine phosphatase receptor type R gene is an early a...
Published: January, 2009
Abstract: BACKGROUND: Tumor development in the human colon is commonly accompanied by epigenetic changes, such as DNA methylation and chromatin modifications... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of the core element responsive to runt-related trans...
Published: January, 2009
Abstract: OBJECTIVE: Type X collagen and runt-related transcription factor 2 (RUNX-2) are known to be important for chondrocyte hypertrophy during skeletal g... Read more »
BEAF regulates cell-cycle genes through the controlled deposition o...
Published: December, 2008
Abstract: Chromatin insulators/boundary elements share the ability to insulate a transgene from its chromosomal context by blocking promiscuous enhancer-prom... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
p53-Responsive micrornas 192 and 215 are capable of inducing cell c...
Published: December, 2008
Abstract: microRNAs provide a novel layer of regulation for gene expression by interfering with the stability and/or translation of specific target mRNAs. Ov... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Myc regulates a transcriptional program that stimulates mitochondri...
Published: December, 2008
Abstract: Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of the remaining met... Read more »
Optimization of experimental design parameters for high-throughput ...
Published: December, 2008
Abstract: High-throughput, microarray-based chromatin immunoprecipitation (ChIP-chip) technology allows in vivo elucidation of transcriptional networks. Howe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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