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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

In vivo chromatin organization of mouse rod photoreceptors correlat...
Published: January, 2010
Abstract: BACKGROUND: The folding of genetic information into chromatin plays important regulatory roles in many nuclear processes and particularly in gene t... Read more »
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Antibody
The core binding factor CBF negatively regulates skeletal muscle te...
Published: January, 2010
Abstract: BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits, Runx1/AML-1 and CBF beta or CBFbeta. CBF was originally ... Read more »
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Bioruptor Antibody
UPF2 is a critical regulator of liver development, function and reg...
Published: January, 2010
Abstract: BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction ... Read more »
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Antibody
The Runx transcriptional co-activator, CBFbeta, is essential for in...
Published: January, 2010
Abstract: BACKGROUND: The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A paucity of heterochromatin at functional human neocentromeres.
Published: January, 2010
Abstract: BACKGROUND: Centromeres are responsible for the proper segregation of replicated chromatids during cell division. Neocentromeres are fully function... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An NF-kappaB-dependent role for JunB in the induction of proinflamm...
Published: January, 2010
Abstract: BACKGROUND: Dendritic cells (DCs) play a key role in the induction of adaptive and memory immune responses. Upon encounter with pathogens, they und... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Monovalent and unpoised status of most genes in undifferentiated ce...
Published: January, 2010
Abstract: BACKGROUND: Increasing evidence demonstrates that stem cells maintain their identities by a unique transcription network and chromatin structure. O... Read more »
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DNA shearing Bioruptor
Retinoic acid protects human breast cancer cells against etoposide-...
Published: January, 2010
Abstract: BACKGROUND: Retinoids, through their cognate nuclear receptors, exert potent effects on cell growth, differentiation and apoptosis, and have signif... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide conserved consensus transcription factor binding motifs...
Published: January, 2010
Abstract: BACKGROUND: DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved con... Read more »
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DNA shearing Bioruptor Antibody
Impact of the DNA methyltransferases expression on the methylation ...
Published: January, 2010
Abstract: Disruption of apoptosis is considered as an important factor aiding tumorigenesis, and aberrant DNA methylation of apoptosis-associated genes could... Read more »
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MeDIP kit
Acetylation of p65 at lysine 314 is important for late NF-kappaB-de...
Published: January, 2010
Abstract: BACKGROUND: NF-kappaB regulates the expression of a large number of target genes involved in the immune and inflammatory response, apoptosis, cell ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimet...
Published: January, 2010
Abstract: The aryl hydrocarbon receptor (AHR) is regarded as an important homeostatic transcriptional regulator within physiological and pathophysiological p... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Assessing the efficiency and significance of Methylated DNA Immunop...
Published: January, 2010
Abstract: BACKGROUND: DNA methylation contributes to the regulation of gene expression during development and cellular differentiation. The recently develope... Read more »
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DNA shearing Bioruptor
Chromatin states of core pluripotency-associated genes in pluripote...
Published: January, 2010
Abstract: Oct4, Nanog and Sox2 constitute a core of transcription factors controlling pluripotency. Differentiation and reprogramming studies have unraveled ... Read more »
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Antibody
Epigenetic silencing of peroxisome proliferator-activated receptor ...
Published: January, 2010
Abstract: The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer path... Read more »
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MeDIP kit
Downstream targets of methyl CpG binding protein 2 and their abnorm...
Published: January, 2010
Abstract: BACKGROUND: The Rett Syndrome (RTT) brain displays regional histopathology and volumetric reduction, with frontal cortex showing such abnormalities... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
CTCF prevents the epigenetic drift of EBV latency promoter Qp.
Published: January, 2010
Abstract: The establishment and maintenance of Epstein-Barr Virus (EBV) latent infection requires distinct viral gene expression programs. These gene express... Read more »
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Chromatin Shearing ChIP-qPCR
Genome-wide analysis of allelic expression imbalance in human prima...
Published: January, 2010
Abstract: Many disease-associated variants identified by genome-wide association (GWA) studies are expected to regulate gene expression. Allele-specific expr... Read more »
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DNA shearing Bioruptor
Global regulator SATB1 recruits beta-catenin and regulates T(H)2 di...
Published: January, 2010
Abstract: In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of beta-catenin, which then associates wit... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Halogenated imidazole derivatives block RNA polymerase II elongatio...
Published: January, 2010
Abstract: BACKGROUND: Aberrant activation of protein kinases is one of the essential oncogenic driving forces inherent to the process of tumorigenesis. The p... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Novel snail1 target proteins in human colon cancer identified by pr...
Published: January, 2010
Abstract: BACKGROUND: The transcription factor Snail1 induces epithelial-to-mesenchymal transition (EMT), a process responsible for the acquisition of invasi... Read more »
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Bioruptor Cell Lysis Western Blot
Nrf2 expression is regulated by epigenetic mechanisms in prostate c...
Published: January, 2010
Abstract: Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many cytoprotective genes. In th... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Nuclear myosin 1 is in complex with mature rRNA transcripts and ass...
Published: January, 2010
Abstract: In rRNA biogenesis, nuclear myosin 1 (NM1) and actin synergize to activate rRNA gene transcription. Evidence that actin is in preribosomal subunits... Read more »
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Bioruptor
Paired hormone response elements predict caveolin-1 as a glucocorti...
Published: January, 2010
Abstract: Glucocorticoids act in part via glucocorticoid receptor binding to hormone response elements (HREs), but their direct target genes in vivo are stil... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Molecular and evolutionary characteristics of the fraction of human...
Published: January, 2010
Abstract: BACKGROUND: The mode of evolution of the highly homogeneous Higher-Order-Repeat-containing alpha satellite arrays is still subject to discussion. T... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis ...
Published: January, 2010
Abstract: Global DNA hypomethylation is a hallmark of cancer cells, but its molecular mechanisms have not been elucidated. Here, we show that the disruption ... Read more »
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MeDIP kit
Impact of DNA demethylation of the G0S2 gene on the transcription o...
Published: December, 2009
Abstract: We recently identified that DNA methylation of the G0S2 gene was significantly more frequent in squamous lung cancer than in non-squamous lung canc... Read more »
Cytotoxic effect and apoptosis induction by silver nanoparticles in...
Published: December, 2009
Abstract: Nanosilver has well-known antibacterial properties, and is widely used in daily life as various medical and general products. In comparison with si... Read more »
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Bioruptor
Muscle inactivation of mTOR causes metabolic and dystrophin defects...
Published: December, 2009
Abstract: Mammalian target of rapamycin (mTOR) is a key regulator of cell growth that associates with raptor and rictor to form the mTOR complex 1 (mTORC1) a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain emb...
Published: December, 2009
Abstract: Embryonic stem cell (ESC) pluripotency is dependent on an intrinsic gene regulatory network centered on Oct4. Propagation of the pluripotent state ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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