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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

UHRF1 coordinates peroxisome proliferator activated receptor gamma ...
Published: January, 2012
Abstract: Peroxisome proliferator-activated receptor gamma (PPARG) inactivation has been identified as an important step in colorectal cancer (CRC) progressi... Read more »
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MeDIP kit
Transcriptional regulation of gene expression during osmotic stress...
Published: January, 2012
Abstract: Although stress can suppress growth and proliferation, cells can induce adaptive responses that allow them to maintain these functions under stress... Read more »
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Chromatin Shearing ChIP-qPCR
Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 ...
Published: January, 2012
Abstract: Carbamazepine (CBZ) is a commonly prescribed antiepileptic drug. Adverse effects and drug-drug interaction are the two major concerns for its clini... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone deacetylase inhibitors sensitize glioblastoma cells to TRAI...
Published: January, 2012
Abstract: Glioblastoma is the most common primary brain tumor with a very poor prognosis, calling for novel treatment strategies. Here, we provide first evid... Read more »
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Chromatin Shearing ChIP-qPCR
Dual role of the ddx5/ddx17 RNA helicases in the control of the pro...
Published: January, 2012
Abstract: Ddx5 and ddx17 are two highly related RNA helicases involved in both transcription and splicing. These proteins coactivate transcription factors in... Read more »
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Chromatin Shearing ChIP-qPCR
Dynamic DNA cytosine methylation in the Populus trichocarpa genome:...
Published: January, 2012
Abstract: ABSTRACT: BACKGROUND: DNA cytosine methylation is an epigenetic modification that has been implicated in many biological processes. However, large... Read more »
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DNA shearing Bioruptor Antibody
Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-...
Published: January, 2012
Abstract: Bmi1 is a key stem cell regulatory gene implicated in the pathogenesis of many aggressive cancers, including medulloblastoma. Overexpression of Bmi... Read more »
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LowCell ChIP kit
A novel retinoblastoma therapy from genomic and epigenetic analyses
Published: January, 2012
Abstract: Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very qui... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genetic inactivation of the polycomb repressive complex 2 in T cell...
Published: January, 2012
Abstract: T cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling. In t... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Activating transcription factor 4-dependent induction of FGF21 duri...
Published: January, 2012
Abstract: Nutrient deprivation or starvation frequently correlates with amino acid limitation. Amino acid starvation initiates a signal transduction cascade ... Read more »
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Chromatin Shearing ChIP-qPCR Bioruptor Plus
Nonoverlapping functions of the Polycomb group Cbx family of protei...
Published: January, 2012
Abstract: Polycomb group proteins are essential regulators of cell fate decisions during embryogenesis. In mammals, at least five different Cbx proteins (Cbx... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RAD tag sequencing as a source of SNP markers in Cynara cardunculus L.
Published: January, 2012
Abstract: ABSTRACT: BACKGROUND: The globe artichoke (Cynara cardunculus L. var. scolymus) genome is relatively poorly explored, especially compared to those... Read more »
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DNA shearing Bioruptor
Epigenetic control of somatostatin and cortistatin expression by β ...
Published: January, 2012
Abstract: β Amyloid, present in senile plaques, has been related largely to neuronal loss in the brain of patients with Alzheimer's disease. However, how neu... Read more »
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LowCell ChIP kit
Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA...
Published: January, 2012
Abstract: Aberrant neocortical DNA methylation has been suggested to be a pathophysiological contributor to psychotic disorders. Recently, a growth arrest an... Read more »
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Antibody 5mC (C15200081)
dSet1 is the main H3K4 di- and tri-methyltransferase throughout Dro...
Published: January, 2012
Abstract: In eukaryotes, the post-translational addition of methyl groups to histone H3 lysine 4 (H3K4) plays key roles in maintenance and establishment of a... Read more »
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Bioruptor
The prosensory function of sox2 in the chicken inner ear relies on ...
Published: January, 2012
Abstract: The proneural gene Atoh1 is crucial for the development of inner ear hair cells and it requires the function of the transcription factor Sox2 throu... Read more »
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Chromatin Shearing ChIP-qPCR
Novel transcriptional targets of the SRY-HMG box transcription fact...
Published: January, 2012
Abstract: The HMG box transcription factor SOX4 involved in neuronal development is amplified and overexpressed in a subset of lung cancers, suggesting that ... Read more »
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Antibody
The cytokine temporal profile in rat cortex after controlled cortic...
Published: January, 2012
Abstract: Cerebral inflammatory responses may initiate secondary cascades following traumatic brain injury (TBI). Changes in the expression of both cytokines... Read more »
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Bioruptor Tissue Homogenization
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels im...
Published: December, 2011
Abstract: The TET family of FE(II) and 2-oxoglutarate-dependent enzymes (Tet1/2/3) promote DNA demethylation by converting 5-methylcytosine to 5-hydroxymethy... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
High-Mobility Group A1 Protein: A New Coregulator of Peroxisome Pro...
Published: December, 2011
Abstract: Rationale:The nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) is an important regulator of gene transcription in vascular cel... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
Genotoxic effects of silver nanoparticles stimulated by oxidative s...
Published: December, 2011
Abstract: Many classes of silver nanoparticles (Ag-NPs) have been synthesized and widely applied, but the genotoxicity of Ag-NPs and the factors leading to g... Read more »
The little elongation complex regulates small nuclear RNA transcrip...
Published: December, 2011
Abstract: Eleven-nineteen lysine-rich leukemia (ELL) participates in the super elongation complex (SEC) with the RNA polymerase II (Pol II) CTD kinase P-TEFb... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Adaptation to P element transposon invasion in Drosophila melanogas...
Published: December, 2011
Abstract: Transposons evolve rapidly and can mobilize and trigger genetic instability. Piwi-interacting RNAs (piRNAs) silence these genome pathogens, but it ... Read more »
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DNA shearing Bioruptor
Caenorhabditis elegans Heterochromatin Protein 1 (HPL-2) links deve...
Published: December, 2011
Abstract: ABSTRACT: BACKGROUND: Heterochromatin protein 1 (HP1) family proteins have a well-characterized role in heterochromatin packaging and gene regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of a proximal Sp1 response element in the mouse Dl...
Published: December, 2011
Abstract: ABSTRACT: BACKGROUND: DLK2 is an EGF-like membrane protein, closely related to DLK1, which is involved in adipogenesis. Both proteins interact wit... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A small molecule differentiation inducer increases insulin producti...
Published: December, 2011
Abstract: New drugs for preserving and restoring pancreatic β-cell function are critically needed for the worldwide epidemic of type 2 diabetes and the cure ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Second order regulator Collier directly controls intercalary-specif...
Published: December, 2011
Abstract: In Drosophila, trunk metamerization is established by a cascade of segmentation gene activities: the gap genes, the pair rule genes, and the segmen... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Regulation of cell growth by Notch signaling and its differential r...
Published: December, 2011
Abstract: Cancer stem cells (CSCs) are postulated to be a small subset of tumor cells with tumor-initiating ability that shares features with normal tissue-s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
cAMP response element-binding protein is a primary hub of activity-...
Published: December, 2011
Abstract: Long-lasting forms of neuronal plasticity require de novo gene expression, but relatively little is known about the events that occur genome-wide i... Read more »
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Bioruptor Cell Lysis Western Blot
Prepatterning of developmental gene expression by modified histones...
Published: December, 2011
Abstract: A hallmark of anamniote vertebrate development is a window of embryonic transcription-independent cell divisions before onset of zygotic genome act... Read more »
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Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)

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