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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

A workflow for genome-wide mapping of archaeal transcription factor...
Published: February, 2012
Abstract: Deciphering the structure of gene regulatory networks across the tree of life remains one of the major challenges in postgenomic biology. We presen... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Research Resource: The Pdx1 Cistrome of Pancreatic Islets.
Published: February, 2012
Abstract: The homeodomain transcription factor pancreas duodenal homeobox 1 (Pdx1, also known as insulin promoter factor 1) is a master regulator of pancreas... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target S...
Published: February, 2012
Abstract: Polycomb-repressive complex 1 (PRC1) has a central role in the regulation of heritable gene silencing during differentiation and development. PRC1 ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Dataset integration identifies transcriptional regulation of microR...
Published: February, 2012
Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) is a key transcription factor in mammalian adipogenesis. Genome-wide approaches have identifie... Read more »
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Chromatin Shearing ChIP-qPCR
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive com...
Published: February, 2012
Abstract: HIC1 (Hypermethylated in Cancer 1) is a tumor suppressor gene epigenetically silenced or deleted in many human cancers. HIC1 is involved in regulat... Read more »
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Chromatin Shearing ChIP-qPCR
High-throughput molecular diagnosis of von Willebrand diseaseby nex...
Published: February, 2012
Abstract: Genetic analysis of von Willebrand disease by von Willebrand factor gene sequencing has not yet become routine practice. Nevertheless, the prospect... Read more »
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DNA shearing Bioruptor
The composition and signaling of the IL-35 receptor are unconventio...
Published: February, 2012
Abstract: Interleukin 35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional profile. IL-35 suppresses T cell prolif... Read more »
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Chromatin Shearing ChIP-qPCR
Heritable genome-wide variation of gene expression and promoter met...
Published: February, 2012
Abstract: ABSTRACT: BACKGROUND: Variations in gene expression, mediated by epigenetic mechanisms, may cause broad phenotypic effects in animals. However, it ... Read more »
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Antibody
Three-dimensional folding and functional organization principles of...
Published: February, 2012
Abstract: Chromosomes are the physical realization of genetic information and thus form the basis for its readout and propagation. Here we present a high-res... Read more »
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DNA shearing Bioruptor
Selective Roles for cAMP Response Element-binding Protein Binding P...
Published: February, 2012
Abstract: Read more »
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Chromatin Shearing ChIP-qPCR
Serial translocation by means of circular intermediates underlies c...
Published: February, 2012
Abstract: Colour sidedness is a dominantly inherited phenotype of cattle characterized by the polarization of pigmented sectors on the flanks, snout and ear ... Read more »
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DNA shearing Bioruptor
Polychlorinated biphenyls affect histone modification pattern in ea...
Published: February, 2012
Abstract: BACKGROUND: The epigenome represents an important target of environmental pollution. Early-life exposure to polychlorinated biphenyls (PCBs) modifi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Western Blot
Heritable transmission of diabetic metabolic memory in zebrafish co...
Published: February, 2012
Abstract: Metabolic memory (MM) is the phenomenon whereby diabetes complications persist and progress after glycemic recovery is achieved. Here, we present d... Read more »
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Antibody
Connexin 43 reverses malignant phenotypes of glioma stem cells by m...
Published: February, 2012
Abstract: Malfunctioned gap junctional intercellular communication (GJIC) has been thought associated with malignant transformation of normal cells. However,... Read more »
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DNA shearing Bioruptor
Nucleolar proteins with altered expression in leukemic cell lines.
Published: February, 2012
Abstract: The function of the nucleolus is intimately connected to cell proliferation, division and growth. Many cancer cells have enlarged nucleoli, and sev... Read more »
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Bioruptor
A quantitative approach towards a better understanding of the dynam...
Published: February, 2012
Abstract: Pork contributes significantly to the public health disease burden caused by Salmonella infections. During the slaughter process pig carcasses can ... Read more »
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Master Mix
Transcription and histone methylation changes correlate with imprin...
Published: February, 2012
Abstract: Genomic imprinting in mammals is controlled by DNA methylation imprints that are acquired in the gametes, at essential sequence elements called 'im... Read more »
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Antibody
Improvement of the redox balance increases L-valine production by C...
Published: February, 2012
Abstract: Production of L-valine under oxygen deprivation conditions by Corynebacterium glutamicum lacking the lactate dehydrogenase gene ldhA and overexpres... Read more »
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Cell Lysis Enzymatic Assay
Conserved molecular interactions within the HBO1 acetyltransferase ...
Published: February, 2012
Abstract: Acetyltransferase complexes of the MYST family with distinct substrate specificities and functions maintain a conserved association with different ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Global DNA hypomethylation coupled to repressive chromatin domain f...
Published: February, 2012
Abstract: While genetic mutation is a hallmark of cancer, many cancers also acquire epigenetic alterations during tumorigenesis including aberrant DNA hyperm... Read more »
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DNA shearing Bioruptor Antibody
Tissue-specific analysis of chromatin state identifies temporal sig...
Published: February, 2012
Abstract: Chromatin modifications are associated with many aspects of gene expression, yet their role in cellular transitions during development remains elus... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Epigenetic regulation of the latency-associated region of Marek's d...
Published: February, 2012
Abstract: Meq is the major Marek's disease virus (MDV)-encoded oncoprotein and is essential for T-cell lymphomagenesis. Meq and several noncoding RNAs, inclu... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Histone deacetylase 6 (HDAC6) is an essential modifier of glucocort...
Published: February, 2012
Abstract: In the current study, we investigated the importance of histone deacetylase (HDAC)6 for glucocorticoid receptor-mediated effects on glucose metabol... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit
IL-31 regulates differentiation and filaggrin expression in human o...
Published: February, 2012
Abstract: BACKGROUND: Atopic dermatitis (AD) is an inflammatory skin disease affecting 10% to 20% of children and 1% to 3% of adults in industrialized countr... Read more »
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Master Mix
Molecular analysis of enhancer RNAs and chromatin modifications in ...
Published: February, 2012
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Antibody
Searching for novel molecular targets of chronic rejection in an or...
Published: February, 2012
Abstract: BACKGROUND: Chronic rejection (CR) is the main reason for the limited survival rates among lung transplant (LT) recipients. There remains no effect... Read more »
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Master Mix
Translocation capture sequencing: a method for high throughput mapp...
Published: January, 2012
Abstract: Chromosomal translocations require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and a... Read more »
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DNA shearing Bioruptor
Genome-wide landscape of liver X receptor chromatin binding and gen...
Published: January, 2012
Abstract: ABSTRACT: BACKGROUND: The liver X receptors (LXRs) are oxysterol sensing nuclear receptors with multiple effects on metabolism and immune cells. Ho... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Spt5 C-terminal region recruits yeast 3’-RNA cleavage factor I
Published: January, 2012
Abstract: During transcription elongation, RNA polymerase (Pol) II binds the general elongation factor Spt5. Spt5 contains a repetitive C-terminal region (CT... Read more »
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Chromatin Shearing ChIP-qPCR
Phosphorylation of BRN2 modulates its interaction with the Pax3 pro...
Published: January, 2012
Abstract: MITF-M and PAX3 are proteins central to the establishment and transformation of the melanocyte lineage. They control various cellular mechanisms, i... Read more »

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