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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice d...
Published: July, 2017
Abstract: Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chr... Read more »
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Antibody IP-Star Compact
CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential...
Published: July, 2017
Abstract: Plasmodium falciparum relies on monoallelic expression of 1 of 60 var virulence genes for antigenic variation and host immune evasion. Each var gen... Read more »
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Microplex Library Preparation kit
The epigenetic architecture at gene promoters determines cell type-...
Published: July, 2017
Abstract: Synovial fibroblasts (SF) drive inflammation and joint destruction in chronic arthritis. Here we show that SF possess a distinct type of LPS tolera... Read more »
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ChIP-seq
Dynamic Reorganization of Chromatin Accessibility Signatures during...
Published: July, 2017
Abstract: Replicating Lgr5+ stem cells and quiescent Bmi1+ cells behave as intestinal stem cells (ISCs) in vivo. Disrupting Lgr5+ ISCs triggers epitheli... Read more »
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Antibody
MAPK-triggered chromatin reprogramming by histone deacetylase in pl...
Published: July, 2017
Abstract: Background Microbial-associated molecular patterns activate several MAP kinases, which are major regulators of the innate immune response in A... Read more »
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IPure kit
Genome-wide mapping and analysis of aryl hydrocarbon receptor (AHR)...
Published: July, 2017
Abstract: The aryl hydrocarbon receptor (AHR) mediates the toxic actions of environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD... Read more »
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Microplex Library Preparation kit
SOX2 as a New Regulator of HPV16 Transcription
Published: July, 2017
Abstract: Persistent infections with high-risk human papillomavirus (HPV) constitute the main risk factor for cervical cancer development. HPV16 is the most ... Read more »
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ChIP-qPCR
The RNA helicase DHX9 establishes nucleolar heterochromatin, and th...
Published: July, 2017
Abstract: Long non-coding RNAs (lncRNAs) have been implicated in the regulation of chromatin conformation and epigenetic patterns. lncRNA expression levels a... Read more »
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Antibody
Pramel7 mediates ground-state pluripotency through proteasomal-epig...
Published: July, 2017
Abstract: Naive pluripotency is established in preimplantation epiblast. Embryonic stem cells (ESCs) represent the immortalization of naive pluripotency. 2i ... Read more »
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Antibody
The complex genetics of hypoplastic left heart syndrome
Published: July, 2017
Abstract: Congenital heart disease (CHD) affects up to 1% of live births. Although a genetic etiology is indicated by an increased recurrence risk, sporadic ... Read more »
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ChIP-seq
Natural and induced loss of function mutations in SlMBP21 MADS-box ...
Published: June, 2017
Abstract: Abscission is the mechanism by which plants disconnect unfertilized flowers, ripe fruits, senescent or diseased organs from the plant. In tomato, p... Read more »
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IP-Star Compact
Methylome analysis of extreme chemoresponsive patients identifies n...
Published: June, 2017
Abstract: BACKGROUND: Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of... Read more »
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MethylCap
Chromatin Immunoprecipitation (ChIP) in Mouse T-cell Lines
Published: June, 2017
Abstract: Signaling pathways regulate gene expression programs via the modulation of the chromatin structure at different levels, such as by post-translation... Read more »
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Antibody
Inhibition of Histone H3K9 Methylation by BIX-01294 Promotes Stress...
Published: June, 2017
Abstract: Microspore embryogenesis is a process of cell reprogramming, totipotency acquisition and embryogenesis initiation, induced in vitro by stress treat... Read more »
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Antibody
The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth cont...
Published: June, 2017
Abstract: Background Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whil... Read more »
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IPure kit
Neuropeptide Y expression marks partially differentiated β cells in...
Published: June, 2017
Abstract: β Cells are formed in embryonic life by differentiation of endocrine progenitors and expand by replication during neonatal life, followed by t... Read more »
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Antibody
Performance of four modern whole genome amplification methods for c...
Published: June, 2017
Abstract: Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of c... Read more »
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IP-Star Compact
DNMT and HDAC inhibitors induce cryptic transcription start sites e...
Published: June, 2017
Abstract: Several mechanisms of action have been proposed for DNA methyltransferase and histone deacetylase inhibitors (DNMTi and HDACi), primarily based on ... Read more »
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Antibody IP-Star Compact
Dynamics of DNA methylomes underlie oyster development
Published: June, 2017
Abstract: DNA methylation is a critical epigenetic regulator of development in mammals and social insects, but its significance in development outside these ... Read more »
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MagMeDIP kit
Histone deacetylase inhibitors potentiate photodynamic therapy in c...
Published: June, 2017
Abstract: Background Hypericin-mediated photodynamic therapy (HY-PDT) has recently captured increased attention as an alternative minimally invasive ant... Read more »
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Antibody IP-Star Compact
HDAC1 links early life stress to schizophrenia-like phenotypes
Published: June, 2017
Abstract: Schizophrenia is a devastating disease that arises on the background of genetic predisposition and environmental risk factors, such as early life s... Read more »
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Antibody
ALDH1A3 is epigenetically regulated during melanocyte transformatio...
Published: June, 2017
Abstract: Despite the promising targeted and immune-based interventions in melanoma treatment, long-lasting responses are limited. Melanoma cells present an ... Read more »
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MethylCap
ICF-specific DNMT3B dysfunction interferes with intragenic regulati...
Published: June, 2017
Abstract: Hypomorphic mutations in DNA-methyltransferase DNMT3B cause majority of the rare disorder Immunodeficiency, Centromere instability and Facial anoma... Read more »
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Antibody
Transcription Factor Interplay between LEAFY and APETALA1/CAULIFLOW...
Published: June, 2017
Abstract: The transcription factors LEAFY (LFY) and APETALA1 (AP1), together with the AP1 paralog CAULIFLOWER (CAL), control the onset of flower development ... Read more »
A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognit...
Published: June, 2017
Abstract: The balance between detrimental, pro-aging, often stochastic processes and counteracting homeostatic mechanisms largely determines the progression ... Read more »
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LowCell ChIP kit
CRISPR-Cas9 Structures and Mechanisms
Published: May, 2017
Abstract: Many bacterial CRISPR-Cas systems employ the dual-RNA-guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by in... Read more »
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Article alert
MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylati...
Published: May, 2017
Abstract: Background DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent s... Read more »
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MagMeDIP kit
ASXL2 is essential for haematopoiesis and acts as a haploinsufficie...
Published: May, 2017
Abstract: Additional sex combs-like (ASXL) proteins are mammalian homologues of additional sex combs (Asx), a regulator of trithorax and polycomb function in... Read more »
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IP-Star Compact
Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription f...
Published: May, 2017
Abstract: Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at lysine 27 (H3K27ac) are correlated with transcriptionally enga... Read more »
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Antibody
Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcr...
Published: May, 2017
Abstract: Monocytes are circulating, short-lived mononuclear phagocytes, which in mice and man comprise two main subpopulations. MurineLy6C+ monocytes displa... Read more »
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Bioruptor

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