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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Single-cell-resolved dynamics of chromatin architecture delineate c...
Published: January, 2022
Abstract: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While man... Read more »
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Bioruptor True MicroChIP kit
Human centromere formation activates transcription and opens chroma...
Published: January, 2022
Abstract: Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments l... Read more »
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Antibody
Pre-configuring chromatin architecture with histone modifications g...
Published: January, 2022
Abstract: The gene activity underlying cell differentiation is regulated by a diverse set of transcription factors (TFs), histone modifications, chromatin st... Read more »
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Antibody
NuA4 and H2A.Z control environmental responses and autotrophicgrowt...
Published: January, 2022
Abstract: Nucleosomal acetyltransferase of H4 (NuA4) is an essential transcriptional coactivator in eukaryotes, but remains poorly characterized in plants. H... Read more »
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Antibody Microplex Library Preparation kit
Developmental and Injury-induced Changes in DNA Methylation inRegen...
Published: January, 2022
Abstract: Background Because some of its CNS neurons (e.g., retinal ganglion cells after optic nerve crush (ONC)) regenerate axons throughout life, whereas o... Read more »
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iDeal ChIP-seq Kit for Histones hMeDIP
DNMT1 regulates the timing of DNA methylation by DNMT3 in anenzymat...
Published: January, 2022
Abstract: DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of o... Read more »
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Antibody
The genome sequence of the brimstone moth, Opisthograptis luteolata...
Published: January, 2022
Abstract: We present a genome assembly from an individual male (the brimstone moth; Arthropoda; Insecta; Lepidoptera; Geometridae). The genome sequence is 36... Read more »
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Megaruptor
MGcount: a total RNA-seq quantification tool to address multi-mappi...
Published: January, 2022
Abstract: Background Total-RNA sequencing (total-RNA-seq) allows the simultaneous study of both the coding and the non-coding transcriptome. Yet, computation... Read more »
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D-Plex small RNA-seq
Coordinated glucocorticoid receptor and MAFB action inducestoleroge...
Published: January, 2022
Abstract: Abstract Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the glucocorticoid receptor (GR). Dendritic cells (DC... Read more »
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Antibody IPure kit
Improved chromosome-level genome assembly of the Glanville fritilla...
Published: January, 2022
Abstract: Abstract Background The Glanville fritillary (Melitaea cinxia) butterfly is a model system for metapopulation dynamics research in fragmented lands... Read more »
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Megaruptor
Single amino-acid mutation in a Drosoph ila melanogaster ribosomalp...
Published: January, 2022
Abstract: The ribosomal protein uL11 is located at the basis of the ribosome P-stalk and plays a paramount role in translational efficiency. In addition, no ... Read more »
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Antibody
Sp1-Induced SETDB1 Overexpression Transcriptionally InhibitsHPGD in...
Published: January, 2022
Abstract: Gastric cancer (GC) has high morbidity and mortality, the cure rate of surgical treatment and drug chemotherapy is not ideal. Therefore, developmen... Read more »
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IP-Star Compact iDeal ChIP-seq Kit for Histones
Three classes of epigenomic regulators converge to hyperactivate th...
Published: January, 2022
Abstract: The formation of a diploid zygote is a highly complex cellular process that is entirely controlled by maternal gene products stored in the egg cyto... Read more »
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Microplex Library Preparation kit
Bone marrow age dictates clonality of smooth muscle-derived cells i...
Published: January, 2022
Abstract: Aging is the predominant risk factor for atherosclerosis, the leading cause of death. Rare smooth muscle cells (SMCs) clonally expand giving rise t... Read more »
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hMeDIP
Mod(mdg4) variants repress telomeric retrotransposon HeT-A byblocki...
Published: January, 2022
Abstract: Telomeres in Drosophila are composed of sequential non-LTR retrotransposons: HeT-A, TART , and TAHRE . Although they are repressed by the piRNA pat... Read more »
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Antibody
The genome sequence of Gymnosoma rotundatum (Linnaeus, 1758), apara...
Published: January, 2022
Abstract: We present a genome assembly from an individual male (Arthropoda; Insecta; Diptera; Tachinidae). The genome sequence is 779 megabases in span. The ... Read more »
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Megaruptor
Integrating SNPs-based genetic risk factor with blood epigenomicres...
Published: January, 2022
Abstract: Arsenic (As) contamination in groundwater is responsible for numerous adverse health outcomes among millions of people. Epigenetic alterations are ... Read more »
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MagMeDIP kit IPure kit
Chemokine switch regulated by TGF-β1 in cancer-associated fibroblas...
Published: January, 2022
Abstract: Combining immunogenic cell death-inducing chemotherapies and PD-1 blockade can generate remarkable tumor responses. It is now well established that... Read more »
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Antibody IP-Star Compact
Development and inter-laboratory validation of the VISAGE enhanced ...
Published: January, 2022
Abstract: The analysis of DNA methylation has become an established method for chronological age estimation. This has triggered interest in the forensic comm... Read more »
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Premium Bisulfite Kit
27-Hydroxycholesterol, The Estrogen Receptor Modulator, AltersDNA M...
Published: January, 2022
Abstract: 27-hydroxycholesterol (27-HC) is the first known endogenous selective estrogen receptor modulator (SERM), and its elevation from normal levels is c... Read more »
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Antibody
Loss of KMT2C reprograms the epigenomic landscape in hPSCsresulting...
Published: January, 2022
Abstract: Germline or somatic variation in the family of KMT2 lysine methyltransferases have been associated with a variety of congenital disorders and cance... Read more »
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Antibody
Single cell quantification of ribosome occupancy in early mouse dev...
Published: December, 2021
Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »
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D-Plex small RNA-seq
Androgen receptor and MYC equilibration centralizes on developmenta...
Published: December, 2021
Abstract: Androgen receptor (AR) in prostate cancer (PCa) can drive transcriptional repression of multiple genes including MYC, and supraphysiological androg... Read more »
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Antibody
A predominant enhancer co-amplified with the oncogene is necessary...
Published: December, 2021
Abstract: Amplification and overexpression of the SOX2 oncogene represent a hallmark of squamous cancers originating from diverse tissue types. Here, we find... Read more »
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CRISPR
The long noncoding RNA H19 regulates tumor plasticity inneuroendocr...
Published: December, 2021
Abstract: Neuroendocrine (NE) prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer (PCa) arising either de novo or from transdi... Read more »
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Antibody
Sevoflurane induces inflammation in primary hippocampal neurons byr...
Published: December, 2021
Abstract: Postoperative cognitive dysfunction (POCD) is a normal condition that develops after surgery with anesthesia, leading to deterioration of cognitive... Read more »
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iDeal ChIP-qPCR
Epigenetic Silencing of OR and TAS2R Genes Expression inHuman Orbit...
Published: December, 2021
Abstract: Modulation of brain olfactory (OR) and taste receptors (TASR) expression was recently reported in neurological diseases. We explored the possible e... Read more »
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Antibody
Gene bookmarking by the heat shock transcription factor programs th...
Published: December, 2021
Abstract: Maternal stress can have long-lasting epigenetic effects on offspring. To examine how epigenetic changes are triggered by stress, we examined the e... Read more »
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Antibody
Examining age-dependent DNA methylation patterns and gene expressio...
Published: December, 2021
Abstract: DNA methylation is a well-characterized epigenetic modification involved in numerous molecular and cellular functions. Methylation patterns have al... Read more »
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MagMeDIP kit
Cancer Detection and Classification by CpG Island Hypermethylation ...
Published: November, 2021
Abstract: Cell-free DNA (cfDNA) methylation has emerged as a promising biomarker for early cancer detection, tumor type classification, and treatment respons... Read more »
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MethylCap kit

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