Publications,References

The Arabidopsis LDL1/2-HDA6 histone modification complex is functio...
Published: August, 2018

Abstract: In Arabidopsis, the circadian clock central oscillator genes are important cellular components to generate and maintain circadian rhythms. There is... Read more »

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Antibody

Canonical PRC2 function is essential for mammary gland development ...
Published: August, 2018

Abstract: Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone ... Read more »

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Antibody

The histone demethylase Jarid1b mediates angiotensin II-induced end...
Published: August, 2018

Abstract: AIM: The histone demethylase Jarid1b limits gene expression by removing the active methyl mark from histone3 lysine4 at gene promoter regions. A va... Read more »

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ChIP-qPCR

Long-read sequence capture of the haemoglobin gene clusters across ...
Published: August, 2018

Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »

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Megaruptor

The effect of Jun dimerization on neurite outgrowth and motif binding.
Published: August, 2018

Abstract: Axon regeneration is a necessary step toward functional recovery after spinal cord injury. The AP-1 transcription factor c-Jun has long been known ... Read more »

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ChIP-qPCR

The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic t...
Published: August, 2018

Abstract: Chromatin remodeler Brahma related gene 1 (BRG1) is silenced in approximately 10% of human pancreatic ductal adenocarcinomas (PDAs). We previously ... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Novel dual regulators of Pseudomonas aeruginosa essential for produ...
Published: August, 2018

Abstract: Gene regulation network in Pseudomonas aeruginosa is complex. With a relatively large genome (6.2 Mb), there is a significant portion of genes that... Read more »

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Antibody

Identification of miR-379/miR-656 (C14MC) cluster downregulation an...
Published: August, 2018

Abstract: INTRODUCTION: Although role of individual microRNAs (miRNAs) in the pathogenesis of gliomas has been well studied, their role as a clustered remain... Read more »

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IPure kit

Automethylation-induced conformational switch in Clr4 (Suv39h) main...
Published: August, 2018

Abstract: Histone H3 lysine 9 methylation (H3K9me) mediates heterochromatic gene silencing and is important for genome stability and the regulation of gene e... Read more »

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Antibody True MicroChIP kit

Epigenetic regulation of brain region-specific microglia clearance ...
Published: August, 2018

Abstract: The rapid elimination of dying neurons and nonfunctional synapses in the brain is carried out by microglia, the resident myeloid cells of the brain... Read more »

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IPure kit

HIV-2/SIV viral protein X counteracts HUSH repressor complex.
Published: August, 2018

Abstract: To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2) have evolved auxiliary proteins that target cell restrictio... Read more »

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Antibody HighCell ChIP kit

Atopic asthma after rhinovirus-induced wheezing is associated with ...
Published: August, 2018

Abstract: Children with rhinovirus-induced severe early wheezing have an increased risk of developing asthma later in life. The exact molecular mechanisms fo... Read more »

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Antibody IP-Star Compact

Methyl-CpG-binding protein 2 mediates antifibrotic effects in scler...
Published: August, 2018

Abstract: OBJECTIVE: Emerging evidence supports a role for epigenetic regulation in the pathogenesis of scleroderma (SSc). We aimed to assess the role of met... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

The transcriptional factor ZEB1 represses Syndecan 1 expression in ...
Published: July, 2018

Abstract: Syndecan 1 (SDC-1) is a cell surface proteoglycan with a significant role in cell adhesion, maintaining epithelial integrity. SDC1 expression is in... Read more »

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Antibody

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-select...
Published: July, 2018

Abstract: ABSTACT: Polycomb-mediated repression of gene expression is essential for development, with a pivotal role played by trimethylation of histone H3 l... Read more »

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Antibody

TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons
Published: July, 2018

Abstract: Testis-specific protein, Y-encoded-like 2 (TSPYL2) is an X-linked gene in the locus for several neurodevelopmental disorders. We have previously sh... Read more »

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Antibody

Wnt receptor Frizzled 8 is a target of ERG in prostate cancer
Published: July, 2018

Abstract: Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men. Many molecular changes have been detailed during PCa progression. ... Read more »

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ChIP-qPCR

The transcription factor Lef1 switches partners from β-catenin to S...
Published: July, 2018

Abstract: Skeletal muscle stem cells (MuSCs), also known as satellite cells, persist in adult mammals by entering a state of quiescence (G) during the early ... Read more »

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LowCell ChIP kit

Longitudinal Effects of Developmental Bisphenol A Exposure on Epige...
Published: July, 2018

Abstract: BACKGROUND: Epigenetic machinery plays an important role in genomic imprinting, a developmental process that establishes parent-of-origin-specific ... Read more »

Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2...
Published: July, 2018

Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both ... Read more »

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Antibody

Embryonic germ cell extracts erase imprinted genes and improve the ...
Published: July, 2018

Abstract: Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies hav... Read more »

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MagMeDIP kit

SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylat...
Published: July, 2018

Abstract: Breast cancer is the most frequently diagnosed malignancy in women worldwide. It is well established that the complexity of carcinogenesis involves... Read more »

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Bioruptor IP-Star Antibody

DNA methylation and genetic degeneration of the Y chromosome in the...
Published: July, 2018

Abstract: BACKGROUND: S. latifolia is a model organism for the study of sex chromosome evolution in plants. Its sex chromosomes include large regions in whic... Read more »

A Somatically Acquired Enhancer of the Androgen Receptor Is a Nonco...
Published: July, 2018

Abstract: Increased androgen receptor (AR) activity drives therapeutic resistance in advanced prostate cancer. The most common resistance mechanism is amplif... Read more »

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Antibody

A LINE1-Nucleolin Partnership Regulates Early Development and ESC I...
Published: July, 2018

Abstract: Transposable elements represent nearly half of mammalian genomes and are generally described as parasites, or "junk DNA." The LINE1 retrotransposon... Read more »

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LowCell ChIP kit

LSD1-ERRα complex requires NRF1 to positively regulate transcriptio...
Published: July, 2018

Abstract: Lysine-specific demethylase 1 (LSD1) exerts dual effects on histone H3, promoting transcriptional repression via Lys4 (H3K4) demethylation or trans... Read more »

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iDeal ChIP-seq Kit for Histones

TRPM7 controls mesenchymal features of breast cancer cells by tensi...
Published: July, 2018

Abstract: Mechanically induced signaling pathways are important drivers of tumor progression. However, if and how mechanical signals affect metastasis or the... Read more »

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Antibody

Enhancer-driven transcriptional regulation is a potential key deter...
Published: June, 2018

Abstract: Obesity is characterized by the excess of body fat leading to impaired health. Abdominal fat is particularly harmful and is associated with cardiov... Read more »

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Microplex Library Preparation kit

An Integrated and Semiautomated Microscaled Approach to Profile Cis...
Published: June, 2018

Abstract: Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory ... Read more »

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Antibody IP-Star Compact True MicroChIP kit

Gene promoter and exon DNA methylation changes in colon cancer deve...
Published: June, 2018

Abstract: BACKGROUND: DNA mutations occur randomly and sporadically in growth-related genes, mostly on cytosines. Demethylation of cytosines may lead to gene... Read more »

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IP-Star MethylCap

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