Publications,References

Global analysis of DNA methylation and transcription of human repet...
Published: July, 2009

Abstract: Half of the human genome consists of repetitive DNA sequences. Recent studies in various organisms highlight the role of chromatin regulation of re... Read more »

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DNA shearing Bioruptor

CRTC2 (TORC2) contributes to the transcriptional response to fastin...
Published: July, 2009

Abstract: The liver contributes to glucose homeostasis by promoting either storage or production of glucose, depending on the physiological state. The cAMP r... Read more »

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Bioruptor Western Blot Tissue Homogenization

H3K64 trimethylation marks heterochromatin and is dynamically remod...
Published: July, 2009

Abstract: Histone modifications are central to the regulation of all DNA-dependent processes. Lys64 of histone H3 (H3K64) lies within the globular domain at ... Read more »

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Antibody H3K4me3 (C15410003)

Improved Protocols for Illumina Sequencing
Published: July, 2009

Abstract: In this unit, we describe a set of improvements we have made to the standard Illumina protocols to make the sequencing process more reliable in a h... Read more »

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DNA shearing Bioruptor

The human CD6 gene is transcriptionally regulated by RUNX and Ets t...
Published: July, 2009

Abstract: CD6 is a lymphocyte surface receptor involved in lymphocyte activation and differentiation processes that is constitutively expressed on developing... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Metabolic intermediates selectively stimulate transcription factor ...
Published: June, 2009

Abstract: Cells use strategic metabolites to sense the metabolome and accordingly modulate gene expression. Here, we show that the purine and phosphate pathw... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates ...
Published: June, 2009

Abstract: The renin-angiotensin system (RAS) plays a crucial role in cardiovascular and neuronal (patho-)physiology. The angiotensin AT2 receptor (AT2R) seem... Read more »

Phosphorylation of histone H3 Thr-45 is linked to apoptosis.
Published: June, 2009

Abstract: Numerous post-translational modifications have been identified in histones. Most of these occur within the histone tails, but a few have been ident... Read more »

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Bioruptor Cell Lysis Western Blot

Tumor vasculature is regulated by PHD2-mediated angiogenesis and bo...
Published: June, 2009

Abstract: Sustained angiogenesis, through either local sprouting (angiogenesis) or the recruitment of bone marrow-derived cells (BMDCs) (vasculogenesis), is ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A novel mechanism of antagonism between ATP-dependent chromatin rem...
Published: June, 2009

Abstract: Gene expression depends upon the antagonistic actions of chromatin remodeling complexes. While this has been studied extensively for the enzymes th... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone H3 modifications associated with differentiation and long-t...
Published: June, 2009

Abstract: Long-term culture of mesenchymal stem cells leads to a loss of differentiation capacity, the molecular mechanism of which remains not understood. W... Read more »

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Antibody LowCell ChIP kit

Copper accumulation and compartmentalization in mouse fibroblast la...
Published: June, 2009

Abstract: Copper (Cu) is the active center of some enzymes because of its redox-active property, although that property could have harmful effects. Because o... Read more »

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Cell Lysis

The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor ...
Published: June, 2009

Abstract: Genomic integrity is threatened by multiple sources of DNA damage. DNA double-strand breaks (DSBs) are among the most dangerous types of DNA lesion... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Gfi1 integrates progenitor versus granulocytic transcriptional prog...
Published: May, 2009

Abstract: In patients with severe congenital neutropenia (SCN) and mice with growth factor independent-1 (Gfi1) loss of function, arrested myeloid progenitor... Read more »

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Chromatin Shearing ChIP-qPCR

Magnet-guided transduction of mammalian cells and mice using engine...
Published: May, 2009

Abstract: Targeted delivery of therapeutic transgenes into specific cells remains a highly relevant challenge for tissue engineering and future gene-based th... Read more »

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Bioruptor

Characterization of the murine Ephrin-B2 promoter.
Published: May, 2009

Abstract: Eph/ephrin signaling is pivotal in prenatal angiogenesis. Although their role in these processes has been extensively studied the mechanisms contro... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate...
Published: May, 2009

Abstract: Ectopic repression of retinoic acid (RA) receptor target genes by PML/RARA and PLZF/RARA fusion proteins through aberrant recruitment of nuclear co... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Rapid antibody selection by mRNA display on a microfluidic chip.
Published: May, 2009

Abstract: In vitro antibody-display technologies are powerful approaches for isolating monoclonal antibodies from recombinant antibody libraries. However, th... Read more »

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Cell Lysis

A comprehensive analysis of recruitment and transactivation potenti...
Published: April, 2009

Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma. K-Rta and K-bZIP are two major viral transcription facto... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Conversion of cholic acid and chenodeoxycholic acid into their 7-ox...
Published: April, 2009

Abstract: Secondary bile acid-producing bacteria were isolated from human feces to improve our appreciation of the functional diversity and redundancy of the... Read more »

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Cell Lysis Enzymatic Assay

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histo...
Published: March, 2009

Abstract: The linker histone H1 generally participates in the establishment of chromatin structure. However, of the seven somatic H1 isotypes in humans some ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cyclical chromatin looping and transcription factor association on ...
Published: March, 2009

Abstract: The nuclear receptor vitamin D receptor (VDR) is known to associate with three vitamin D response element (VDREs)-containing regions within the CDK... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signal...
Published: March, 2009

Abstract: The C. elegans insulin/IGF-1 signaling (IIS) cascade plays a central role in regulating life span, dauer, metabolism, and stress. The major regulat... Read more »

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Bioruptor Western Blot Tissue Homogenization

Role of 2-oxoglutarate dehydrogenase in brain pathologies involving...
Published: March, 2009

Abstract: Read more »

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Bioruptor Cell Lysis

The dynamic DNA methylomes of double-stranded DNA viruses associate...
Published: March, 2009

Abstract: The natural history of cancers associated with virus exposure is intriguing, since only a minority of human tissues infected with these viruses ine... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide regulon and crystal structure of BlaI (Rv1846c) from My...
Published: March, 2009

Abstract: Comparative genomics with Staphylococcus aureus suggested the existence of a regulatory system governing beta-lactamase (BlaC) production in Mycoba... Read more »

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Bioruptor Chromatin Shearing Cell Lysis

Relics of repeat-induced point mutation direct heterochromatin form...
Published: March, 2009

Abstract: Both RNAi-dependent and -independent mechanisms have been implicated in the establishment of heterochromatin domains, which may be stabilized by fe... Read more »

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Antibody

Genome-wide high throughput analysis of DNA methylation in eukaryotes.
Published: March, 2009

Abstract: Cytosine methylation is the quintessential epigenetic mark. Two well-established methods, bisulfite sequencing and methyl-DNA immunoprecipitation (... Read more »

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Antibody

Differential chromatin marking of introns and expressed exons by H3...
Published: March, 2009

Abstract: Variation in patterns of methylations of histone tails reflects and modulates chromatin structure and function. To provide a framework for the anal... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Temporal regulation of Ath5 gene expression during eye development.
Published: February, 2009

Abstract: During central nervous system development the timing of progenitor differentiation must be precisely controlled to generate the proper number and c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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