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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

An intronic enhancer driven by NF-κB contributes to transcriptional...
Published: November, 2010
Abstract: Peptidylarginine deiminases (PADs) catalyze the conversion of protein-bound arginine to citrulline residues. In human epidermis, where filaggrin is... Read more »
Nucleosome-interacting proteins regulated by DNA and histone methyl...
Published: October, 2010
Abstract: Modifications on histones or on DNA recruit proteins that regulate chromatin function. Here, we use nucleosomes methylated on DNA and on histone H3... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylatio...
Published: October, 2010
Abstract: Evidence links pluripotency to a gene regulatory network organized by the transcription factors Oct4, Nanog and Sox2. Expression of these genes is ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Cell cycle-dependent accumulation of histone H3.3 and euchromatic h...
Published: October, 2010
Abstract: In mammals, DNA methylation is an important epigenetic mark that is associated with gene silencing, particularly in constitutive heterochromatin. H... Read more »
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Chromatin Shearing ChIP-qPCR
ETV1 is a lineage survival factor that cooperates with KIT in gastr...
Published: October, 2010
Abstract: Gastrointestinal stromal tumour (GIST) is the most common human sarcoma and is primarily defined by activating mutations in the KIT or PDGFRA recep... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Combinatorial transcriptional control in blood stem/progenitor cell...
Published: October, 2010
Abstract: Combinatorial transcription factor (TF) interactions control cellular phenotypes and, therefore, underpin stem cell formation, maintenance, and dif... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links ...
Published: October, 2010
Abstract: How regeneration cues are converted into the epigenetic information that controls gene expression in adult stem cells is currently unknown. We iden... Read more »
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Antibody
Comparison of sequencing-based methods to profile DNA methylation a...
Published: October, 2010
Abstract: Analysis of DNA methylation patterns relies increasingly on sequencing-based profiling methods. The four most frequently used sequencing-based tech... Read more »
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DNA shearing Bioruptor
Lysine-specific demethylase 1 regulates the embryonic transcriptome...
Published: October, 2010
Abstract: Lysine-specific demethylase 1 (LSD1), which demethylates mono- and dimethylated histone H3-Lys4 as part of a complex including CoREST and histone d... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional regulation of lipid homeostasis in mycobacteria.
Published: October, 2010
Abstract: Mycolic acids are major components of the cell envelope of mycobacteria, such as Mycobacterium tuberculosis, and play an important role in its arch... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Quantitative comparison of genome-wide DNA methylation mapping tech...
Published: October, 2010
Abstract: DNA methylation plays a key role in regulating eukaryotic gene expression. Although mitotically heritable and stable over time, patterns of DNA met... Read more »
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DNA shearing Bioruptor IP-Star
Effects of atypical antipsychotics and haloperidol on PC12 cells: o...
Published: October, 2010
Abstract: By converting changes in intracellular energy status to changes in cell membrane polarization, ATP-sensitive K(+) (K(ATP)) channels in hypothalamic... Read more »
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Cell Lysis
To remove Quantitative comparison of genome-wide DNA methylation ma...
Published: October, 2010
Abstract: DNA methylation plays a key role in regulating eukaryotic gene expression. Although mitotically heritable and stable over time, patterns of DNA met... Read more »
DNA methylation and Yin Yang-1 repress adenosine A2A receptor level...
Published: October, 2010
Abstract: Adenosine A(2A) receptors (A(2A) Rs) are G-protein coupled receptors that stimulate adenylyl cyclase activity. The most A(2A) Rs-enriched brain reg... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
A chromatin-remodeling protein is a component of fission yeast medi...
Published: September, 2010
Abstract: The multiprotein Mediator complex is an important regulator of RNA polymerase II-dependent genes in eukaryotic cells. In contrast to the situation ... Read more »
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Bioruptor Chromatin Shearing
Distinct epigenetic domains separated by a CTCF bound insulator bet...
Published: September, 2010
Abstract: BACKGROUND: Tumor suppressor gene (TSG) RASSF1A and candidate TSG BLU are two tandem head-to-tail genes located at 3p21.3. We hypothesized that the... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
HAATI survivors replace canonical telomeres with blocks of generic ...
Published: September, 2010
Abstract: The notion that telomeres are essential for chromosome linearity stems from the existence of two chief dangers: inappropriate DNA damage response (... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
SATB1 dictates expression of multiple genes including IL-5 involved...
Published: September, 2010
Abstract: Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer and a transcription factor regulated by interleukin-4 (IL-4) during the e... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin remodeling is required for gene reactivation after decita...
Published: September, 2010
Abstract: The DNA hypomethylating drug decitabine (DAC) reactivates silenced gene expression in cancer and is approved for the treatment of the myelodysplast... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional profiling of day 12 porcine embryonic disc and trop...
Published: September, 2010
Abstract: cDNA derived from trophectoderm (TE) and embryonic disc (ED) of a single day 12 porcine embryo was subjected to next-generation sequencing using th... Read more »
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DNA shearing Bioruptor
Demonstrating polymorphic miRNA-mediated gene regulation in vivo: a...
Published: September, 2010
Abstract: We herein describe the development of a biochemical method to evaluate the effect of single nucleotide polymorphisms (SNPs) in target genes on thei... Read more »
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Bioruptor Cell Lysis Enzymatic Assay
Cellular and pharmacological selectivity of the peroxisome prolifer...
Published: September, 2010
Abstract: The availability of high-affinity agonists for peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) has led to significant advanc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Induction of pluripotency in human cord blood unrestricted somatic ...
Published: September, 2010
Abstract: OBJECTIVE: Generation of induced pluripotent stem (iPS) cells from human cord blood (CB)-derived unrestricted somatic stem cells and evaluation of ... Read more »
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MeDIP kit
Methylation profiling in individuals with uniparental disomy identi...
Published: September, 2010
Abstract: The maternal and paternal genomes possess distinct epigenetic marks that distinguish them at imprinted loci. In order to identify imprinted loci, w... Read more »
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Antibody
The histone H3K36 methyltransferase MES-4 acts epigenetically to tr...
Published: September, 2010
Abstract: Methylation of histone H3K36 in higher eukaryotes is mediated by multiple methyltransferases. Set2-related H3K36 methyltransferases are targeted to... Read more »
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Chromatin Shearing ChIP-qPCR
DNA methylation prevents CTCF-mediated silencing of the oncogene BC...
Published: August, 2010
Abstract: Aberrant DNA methylation commonly occurs in cancer cells where it has been implicated in the epigenetic silencing of tumor suppressor genes. Additi... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Iron regulatory proteins secure mitochondrial iron sufficiency and ...
Published: August, 2010
Abstract: Mitochondria supply cells with ATP, heme, and iron sulfur clusters (ISC), and mitochondrial energy metabolism involves both heme- and ISC-dependent... Read more »
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Bioruptor Cell Lysis
The distribution of active RNA polymerase II along the transcribed ...
Published: August, 2010
Abstract: In order to study the intragenic profiles of active transcription, we determined the relative levels of active RNA polymerase II present at the 3'-... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide mapping of histone H4 serine-1 phosphorylation during s...
Published: August, 2010
Abstract: We previously showed that histone H4 serine-1 phosphorylation (H4S1ph) is evolutionarily conserved during gametogenesis, and contributes to post-me... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Genome-wide profiling of p63 DNA-binding sites identifies an elemen...
Published: August, 2010
Abstract: Heterozygous mutations in p63 are associated with split hand/foot malformations (SHFM), orofacial clefting, and ectodermal abnormalities. Elucidati... Read more »
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Bioruptor Chromatin Shearing ChIP-seq

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