Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The Chromatin Binding Protein HMGN1 Regulates the Expression of Met...
Published: December, 2011

Abstract: High Mobility Group N1 protein (HMGN1), a nucleosomal binding protein that affects the structure and function of chromatin, is encoded by a gene lo... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals ...
Published: December, 2011

Abstract: The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Bio-CAP: a versatile and highly sensitive technique to purify and c...
Published: December, 2011

Abstract: Across vertebrate genomes methylation of cytosine residues within the context of CpG dinucleotides is a pervasive epigenetic mark that can impact g... Read more »

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DNA shearing Bioruptor
Tracheobronchial transplantation with a stem-cell-seeded bioartific...
Published: December, 2011

Abstract: BACKGROUND: Tracheal tumours can be surgically resected but most are an inoperable size at the time of diagnosis; therefore, new therapeutic optio... Read more »

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Antibody LowCell ChIP kit
Comprehensive genome-wide protein-DNA interactions detected at sing...
Published: December, 2011

Abstract: Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins bind throughout a genome. However, DNA contamination and DNA ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
A distinct mechanism for coactivator versus corepressor function by...
Published: December, 2011

Abstract: Histone methyltransferase G9a has been understood primarily as a corepressor of gene expression, but we showed previously that G9a positively regul... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Notch Activation of Jagged1 Contributes to the Assembly of the Arte...
Published: December, 2011

Abstract: BACKGROUND: Notch signaling in vascular smooth muscle precursors is required for smooth muscle differentiation. Jagged1 expression on endothelium ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Pol...
Published: December, 2011

Abstract: Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages requires strict contr... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
DNA methylation regulates the expression of CXCL12 in rheumatoid ar...
Published: December, 2011

Abstract: In the search for specific genes regulated by DNA methylation in rheumatoid arthritis (RA), we investigated the expression of CXCL12 in synovial fi... Read more »

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DNA shearing Bioruptor
A simple method for the parallel deep sequencing of full influenza ...
Published: December, 2011

Abstract: Given the major threat of influenza A to human and animal health, and its ability to evolve rapidly through mutation and reassortment, tools that e... Read more »

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DNA shearing Bioruptor
Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angio...
Published: December, 2011

Abstract: Rationale:Endothelial cells are developmentally derived from angioblasts specified in the mesodermal germ cell layer. The transcription factor etsr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Mechanisms and functions of Tet protein-mediated 5-methylcytosine o...
Published: December, 2011

Abstract: Ten-eleven translocation 1-3 (Tet1-3) proteins have recently been discovered in mammalian cells to be members of a family of DNA hydroxylases that ... Read more »

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Antibody
Novel insights into the regulation of antioxidant-response-element-...
Published: December, 2011

Abstract: A central mechanism in cellular defence against oxidative or electrophilic stress is mediated by transcriptional induction of genes via the ARE (an... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Role of farnesoid X receptor (FXR) in the process of differentiatio...
Published: December, 2011

Abstract: Bone tissue contains bile acids which accumulate from serum and which can be released in large amounts in the bone microenvironment during bone res... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Notch1 binds and induces degradation of Snail in hepatocellular car...
Published: November, 2011

Abstract: BACKGROUND: Hepatocellular carcinoma (HCC) is a common, highly invasive malignant tumor associated with a high mortality rate. We previously report... Read more »

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Bioruptor Cell Lysis Enzymatic Assay
Systematic comparison of three methods for fragmentation of long-ra...
Published: November, 2011

Abstract: Next Generation Sequencing (NGS) technologies are gaining importance in the routine clinical diagnostic setting. It is thus desirable to simplify t... Read more »

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DNA shearing Bioruptor
Distinct Epigenomic Features in End-Stage Failing Human Hearts
Published: November, 2011

Abstract: Background—The epigenome refers to marks on the genome, including DNA methylation and histone modifications, that regulate the expression of underl... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody
Generation and characterization of rat and mouse monoclonal antibod...
Published: November, 2011

Abstract: Methyl CpG binding protein 2 (MeCP2) binds DNA, and has a preference for methylated CpGs and, hence, in cells, it accumulates in heterochromatin. E... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic inactivation of paired box gene 5, a novel tumor suppres...
Published: November, 2011

Abstract: Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function... Read more »
Expression profile of the sphingosine kinase signalling system in t...
Published: November, 2011

Abstract: AIMS: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. Despite its importance, treatment methods are limited and... Read more »

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Bioruptor Cell Lysis Enzymatic Assay
Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of R...
Published: November, 2011

Abstract: Long noncoding RNAs (lncRNAs) are key regulators of chromatin state, yet the nature and sites of RNA-chromatin interaction are mostly unknown. Here... Read more »

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Bioruptor Chromatin Shearing
Prostacyclin Synthase Expression and Epigenetic Regulation in Nonsm...
Published: November, 2011

Abstract: BACKGROUND: Prostacyclin synthase (PGIS) metabolizes prostaglandin H(2), into prostacyclin. This study aimed to determine the expression profile o... Read more »
Pre-B cell to macrophage transdifferentiation without significant p...
Published: November, 2011

Abstract: Transcription factor-induced lineage reprogramming or transdifferentiation experiments are essential for understanding the plasticity of differenti... Read more »

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Antibody MethylCap
Human tRNA genes function as chromatin insulators
Published: November, 2011

Abstract: nsulators help separate active chromatin domains from silenced ones. In yeast, gene promoters act as insulators to block the spread of Sir and HP1 ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The forkhead transcription factor FOXK2 promotes AP-1-mediated tran...
Published: November, 2011

Abstract: The transcriptional control circuitry in eukaryotic cells is complex and is orchestrated by combinatorially acting transcription factors. Forkhead ... Read more »

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Bioruptor Chromatin Shearing
FOG-1 and GATA-1 act sequentially to specify definitive megakaryocy...
Published: November, 2011

Abstract: The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for the myeloid and lymph... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
YY1 associates with the macrosatellite DXZ4 on the inactive X chrom...
Published: November, 2011

Abstract: DXZ4 is an X-linked macrosatellite composed of 12-100 tandemly arranged 3-kb repeat units. In females, it adopts opposite chromatin arrangements at... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Gene expression and epigenetic changes by furan in rat liver.
Published: November, 2011

Abstract: Furan, a widely used industrial compound, has been found in a number of heated food items. Furan is carcinogenic to rats and mice, but the mechanis... Read more »

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MagMeDIP kit
Rapid mapping and identification of mutations in Caenorhabditis ele...
Published: November, 2011

Abstract: Forward genetic screens provide a powerful approach for inferring gene function on the basis of the phenotypes associated with mutated genes. Howev... Read more »

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DNA shearing Bioruptor
Osteocalcin gene expression is regulated by wild-type p53.
Published: November, 2011

Abstract: The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA dam... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

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