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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Transcriptome-wide dynamics of extensive m6A mRNA methylation durin...
Published: March, 2019
Abstract: Malaria pathogenesis results from the asexual replication of Plasmodium falciparum within human red blood cells, which relies on a precisely timed ... Read more »
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Bioruptor Microplex Library Preparation kit
R-Loops Enhance Polycomb Repression at a Subset of Developmental Re...
Published: March, 2019
Abstract: R-loops are three-stranded nucleic acid structures that form during transcription, especially over unmethylated CpG-rich promoters of active genes.... Read more »
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Antibody
Maintenance of MYC expression promotes de novo resistance to BET br...
Published: March, 2019
Abstract: The BET bromodomain protein BRD4 is a chromatin reader that regulates transcription, including in cancer. In prostate cancer, specifically, the ant... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Ezh2 controls development of natural killer T cells, which cause sp...
Published: March, 2019
Abstract: BACKGROUND: Natural killer T (NKT) cells express a T-cell receptor that recognizes endogenous and environmental glycolipid antigens. Several subset... Read more »
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Antibody
Genetic, Inflammatory, and Epithelial Cell Differentiation Factors ...
Published: March, 2019
Abstract: Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that... Read more »
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IP-Star Compact
The epigenetic basis for the impaired ability of adult murine retin...
Published: March, 2019
Abstract: The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenerate the entire retina, a trait known to be absent in ... Read more »
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Antibody IP-Star Compact True MicroChIP kit
Chromatin activity at GWAS loci identifies T cell states driving co...
Published: March, 2019
Abstract: Complex immune disease variants are enriched in active chromatin regions of T cells and macrophages. However, whether these variants function in sp... Read more »
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Bioruptor iDeal ChIP-seq Kit for Histones
MicroRNAs and Transplantation.
Published: March, 2019
Abstract: miRNAs, ∼20 to 22 nucleotide single-stranded RNA species that play a pivotal role in the regulation of protein-coding genes, are emerging as ro... Read more »
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CATS
NF-κB p65 dimerization and DNA-binding is important for inflammator...
Published: March, 2019
Abstract: Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-... Read more »
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Microplex Library Preparation kit
H3K27me3 is an epigenetic barrier while KDM6A overexpression improv...
Published: March, 2019
Abstract: Aberrant epigenetic reprogramming is a major factor of developmental failure of cloned embryos. Histone H3 lysine 27 trimethylation (H3K27me3), a h... Read more »
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Antibody
Long-term evaluation of AAV-CRISPR genome editing for Duchenne musc...
Published: March, 2019
Abstract: Duchenne muscular dystrophy (DMD) is a monogenic disorder and a candidate for therapeutic genome editing. There have been several recent reports of... Read more »
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CRISPR
One-step generation of modular CAR-T cells with AAV-Cpf1.
Published: March, 2019
Abstract: Immune-cell engineering opens new capabilities for fundamental immunology research and immunotherapy. We developed a system for efficient generatio... Read more »
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CRISPR
Genomewide analysis of 6-methyladenine DNA in peripheral blood mono...
Published: March, 2019
Abstract: AIM: The aim of this paper is to explore the expression of 6-methyladenine (6mA) DNA and to elucidate its gene regulation role in systemic lupus er... Read more »
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Antibody
The alternative reality of plant mitochondrial DNA
Published: March, 2019
Abstract: Plant mitochondrial genomes are usually assembled and displayed as circular maps based on the widely-held assumption that circular genome molecules... Read more »
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Megaruptor
Differential regulation of RNA polymerase III genes during liver re...
Published: February, 2019
Abstract: Mouse liver regeneration after partial hepatectomy involves cells in the remaining tissue synchronously entering the cell division cycle. We have u... Read more »
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Microplex Library Preparation kit
A critical but divergent role of PRDM14 in human primordial germ ce...
Published: February, 2019
Abstract: PRDM14 is a crucial regulator of mouse primordial germ cells (mPGC), epigenetic reprogramming and pluripotency, but its role in the evolutionarily ... Read more »
Environmental Toxicant Induced Epigenetic Transgenerational Inherit...
Published: February, 2019
Abstract: Prostate diseases include prostate cancer, which is the second most common male neoplasia, and benign prostatic hyperplasia (BPH), which affects ap... Read more »
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Antibody
CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoiet...
Published: February, 2019
Abstract: In this study, we demonstrate that, among all five CBX Polycomb proteins, only CBX7 possesses the ability to control self-renewal of human hematopo... Read more »
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Antibody Microplex Library Preparation kit
Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Mic...
Published: February, 2019
Abstract: The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However... Read more »
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Antibody
EZH2 is overexpressed in transitional preplasmablasts and is involv...
Published: February, 2019
Abstract: Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using m... Read more »
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Antibody IPure kit IP-Star Compact True MicroChIP kit iDeal ChIP-seq Kit for Transcription Factors
A cell cycle-coordinated Polymerase II transcription compartment en...
Published: February, 2019
Abstract: Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed until the mid-blastu... Read more »
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Antibody
Crosstalk Between Glucocorticoid Receptor and Early-growth Response...
Published: February, 2019
Abstract: The brain-derived neurotrophic factor (BDNF) is a key player in brain functions such as synaptic plasticity, stress, and behavior. Its gene structu... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Adolescent social isolation affects parvalbumin expression in the m...
Published: February, 2019
Abstract: Altered parvalbumin (PV) expression is observed in the prefrontal cortex of subjects with schizophrenia. Environmental context, particularly during... Read more »
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ChIP-qPCR
Developmental regulation of DNA cytosine methylation at the immunog...
Published: February, 2019
Abstract: DNA cytosine methylation is involved in the regulation of gene expression during development and its deregulation is often associated with disease.... Read more »
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Premium Bisulfite Kit
Interleukin-22 protects intestinal stem cells against genotoxic str...
Published: February, 2019
Abstract: Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from... Read more »
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Beads
Characterizing the Major Structural Variant Alleles of the Human Ge...
Published: January, 2019
Abstract: In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read sequence data and analyzed SVs for fifteen... Read more »
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Megaruptor
Complete Genome Sequence and Methylome Analysis of Micrococcus lute...
Published: January, 2019
Abstract: Micrococcus luteus has been found in a wide range of habitats. We report the complete genome sequence and methylome analysis of strain SA211 isolat... Read more »
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Megaruptor
Replication timing and epigenome remodelling are associated with th...
Published: January, 2019
Abstract: DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and c... Read more »
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Antibody
Evidence of association of circulating epigenetic-sensitive biomark...
Published: January, 2019
Abstract: Circulating biomarkers available in clinical practice do not allow to stratify patients with coronary heart disease (CHD) prior the onset of a clin... Read more »
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MagMeDIP kit
Chromatin-Based Classification of Genetically Heterogeneous AMLs in...
Published: January, 2019
Abstract: Global investigation of histone marks in acute myeloid leukemia (AML) remains limited. Analyses of 38 AML samples through integrated transcriptiona... Read more »
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Antibody

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